Centre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Perth, Australia.
National Centre for Epidemiology and Population Health, Research School of Population Health, Australian National University, Canberra, Australia.
Sci Rep. 2021 Mar 18;11(1):6337. doi: 10.1038/s41598-021-85825-y.
Myopia (near-sightedness) is an important public health issue. Spending more time outdoors can prevent myopia but the long-term association between this exposure and myopia has not been well characterised. We investigated the relationship between time spent outdoors in childhood, adolescence and young adulthood and risk of myopia in young adulthood. The Kidskin Young Adult Myopia Study (KYAMS) was a follow-up of the Kidskin Study, a sun exposure-intervention study of 1776 children aged 6-12 years. Myopia status was assessed in 303 (17.6%) KYAMS participants (aged 25-30 years) and several subjective and objective measures of time spent outdoors were collected in childhood (8-12 years) and adulthood. Index measures of total, childhood and recent time spent outdoors were developed using confirmatory factor analysis. Logistic regression was used to assess the association between a 0.1-unit change in the time outdoor indices and risk of myopia after adjusting for sex, education, outdoor occupation, parental myopia, parental education, ancestry and Kidskin Study intervention group. Spending more time outdoors during childhood was associated with reduced risk of myopia in young adulthood (multivariable odds ratio [OR] 0.82, 95% confidence interval [CI] 0.69, 0.98). Spending more time outdoors in later adolescence and young adulthood was associated with reduced risk of late-onset myopia (≥ 15 years of age, multivariable OR 0.79, 95% CI 0.64, 0.98). Spending more time outdoors in both childhood and adolescence was associated with less myopia in young adulthood.
近视(远视)是一个重要的公共卫生问题。多花时间在户外活动可以预防近视,但这种暴露与近视之间的长期关联尚未得到很好的描述。我们调查了儿童期、青春期和成年早期户外活动时间与成年早期近视风险之间的关系。Kidskin 成年近视研究(KYAMS)是 Kidskin 研究的后续研究,该研究是一项针对 1776 名 6-12 岁儿童的阳光暴露干预研究。在 303 名(17.6%)KYAMS 参与者(年龄 25-30 岁)中评估了近视状况,并在儿童期(8-12 岁)和成年期收集了几项户外活动时间的主观和客观测量值。使用验证性因子分析制定了户外活动总时间、儿童期时间和近期时间的指标。使用逻辑回归评估了时间户外活动指数每增加 0.1 单位与近视风险之间的关联,调整了性别、教育程度、户外职业、父母近视、父母教育程度、祖籍和 Kidskin 研究干预组。儿童期户外活动时间增加与成年早期近视风险降低相关(多变量优势比 [OR] 0.82,95%置信区间 [CI] 0.69,0.98)。青春期和成年早期户外活动时间增加与晚发性近视(≥ 15 岁,多变量 OR 0.79,95% CI 0.64,0.98)风险降低相关。儿童期和青春期都增加户外活动时间与成年早期近视程度降低相关。