Heng Christian Hwee Yee, Snow Martyn, Dave Lee Yee Han
Department of Orthopaedic Surgery, Changi General Hospital, Singapore.
Department of Arthroscopy, The Royal Orthopaedic Hospital, Birmingham, U.K.
Arthrosc Tech. 2021 Feb 8;10(3):e751-e756. doi: 10.1016/j.eats.2020.10.065. eCollection 2021 Mar.
Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds have the versatility to be used in large and irregularly shaped lesions. With correct preparation, they can be applied to lesions on the femoral condyle that may be vertical, or even inverted lesions such as those in the patella. They can be combined with bone marrow aspirate concentrate (BMAC) to provide mesenchymal stem cells (MSCs), thereby avoiding the need for microfracture. This protects the subchondral plate, preventing biomechanical alteration and potentially resulting in improved long-term outcomes. In this article, we demonstrate the utility of injectable scaffolds and their combination with BMAC.
可注射支架增强术是单阶段软骨修复的一种有前景的方式。根据已发表的研究，与单纯微骨折相比，使用支架增强术进行软骨修复在临床结果、放射学填充和组织学修复方面均有改善。可注射支架具有通用性，可用于大的和形状不规则的损伤。经过正确制备后，它们可应用于股骨髁上可能呈垂直状的损伤，甚至可用于诸如髌骨处的倒置损伤。它们可与骨髓抽吸浓缩物（BMAC）联合使用以提供间充质干细胞（MSC），从而避免了微骨折的需要。这保护了软骨下骨板，防止生物力学改变，并可能带来更好的长期结果。在本文中，我们展示了可注射支架及其与BMAC联合使用的效用。
