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老年期的抑郁与生活质量:深入探讨

Depression and quality of life in old age: a closer look.

作者信息

Hussenoeder Felix S, Jentzsch Doreen, Matschinger Herbert, Hinz Andreas, Kilian Reinhold, Riedel-Heller Steffi G, Conrad Ines

机构信息

Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Ph.-Rosenthal-Str. 55, 04103 Leipzig, Germany.

Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.

出版信息

Eur J Ageing. 2020 May 25;18(1):75-83. doi: 10.1007/s10433-020-00573-8. eCollection 2021 Mar.

DOI:10.1007/s10433-020-00573-8
PMID:33746683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7925788/
Abstract

Depressive disorders are among the most widespread mental disorders in old age, with negative consequences for quality of life (QOL). Understanding QOL as a multidimensional construct, in this article we have a closer look on what specific aspects are affected by depression. We used a representative sample of the German population ( = 805) and one of individuals diagnosed with depression ( = 106) to compare QOL using the WHOQOL-BREF and the WHOQOL-OLD. Multivariate analysis showed that individuals diagnosed with depression exhibited lower QOL with regard to WHOQOL-BREF-dimensions physical health, psychological, social relationships and global QOL and with regard to WHOQOL-OLD-facets sensory abilities, past, present, and future activities and social participation. In addition, in the regression analysis, there were no significant differences between individuals with and without depression with regard to environment (WHOQOL-BREF), autonomy, death and dying, intimacy and overall (WHOQOL-OLD). Associations between depression and QOL in older age are selective in terms of which aspects of QOL are affected. From a methodological perspective, a multidimensional approach to QOL is recommended. From a clinical perspective, our research highlights those areas of QOL that are relevant for health professionals working with older people and that could be the focus of interventions.

摘要

抑郁症是老年人群中最普遍的精神障碍之一,会对生活质量(QOL)产生负面影响。鉴于生活质量是一个多维概念,在本文中,我们将更深入地探讨抑郁症会影响哪些具体方面。我们使用了德国人群的代表性样本(n = 805)和被诊断为抑郁症的个体样本(n = 106),通过世界卫生组织生活质量简表(WHOQOL - BREF)和世界卫生组织老年生活质量量表(WHOQOL - OLD)来比较生活质量。多变量分析表明,被诊断为抑郁症的个体在世界卫生组织生活质量简表的身体健康、心理、社会关系和总体生活质量维度以及世界卫生组织老年生活质量量表的感官能力、过去、现在和未来活动及社会参与方面表现出较低的生活质量。此外,在回归分析中,有抑郁症和无抑郁症的个体在环境(世界卫生组织生活质量简表)、自主性、死亡与临终、亲密关系及总体(世界卫生组织老年生活质量量表)方面没有显著差异。抑郁症与老年人生活质量之间的关联在生活质量受影响的具体方面具有选择性。从方法学角度来看,建议采用多维方法来评估生活质量。从临床角度来看,我们的研究突出了那些对从事老年人工作的卫生专业人员而言与生活质量相关且可能成为干预重点的领域。