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体重指数变化与抑郁症风险之间的关联

The Association Between Changes in Body Mass Index and the Risk of Depression.

作者信息

Wang Jian, Zhang Hong

机构信息

Department of Trauma, Wuhan Mental Health Center, Wuhan, Hubei, China.

Department of Psychotherapy, Wuhan Mental Health Center, Wuhan, Hubei, China.

出版信息

Alpha Psychiatry. 2024 Aug 1;25(4):480-484. doi: 10.5152/alphapsychiatry.2024.231314. eCollection 2024 Aug.

Abstract

OBJECTIVE

In recent years, the risk of depression has increased among young people, and changes in body mass index (BMI) during childhood may be important factors in their development. However, the relationship between changes in BMI during childhood and the risk of depression needs further research and exploration.

METHODS

The annual health examination data were collected from Physical Examination Center of Wuhan Mental Health Center Hospital, including 1226 students. The height and weight of students at the age of 11, 14, and 17 were recorded in sequence, and at 18 years old, these students were followed up according to the Hamilton Depression Scale (HAMD) to evaluate the depression. The relationship between BMI trends and depression was analyzed through Logistic regression analysis.

RESULTS

The growth trend of BMI was divided into normal growth, slow growth, and excessive growth. The odds ratio (OR) value for depression in the slow growth was 1.218 (95% CI, 0.995-1.493) compared to the normal growth, which was no significant difference ( = .056). The OR value for depression in the excessive growth was 1.982 (95% CI, 1.243-3.177) compared to the normal growth, which was significant difference ( = .003).

CONCLUSION

The rapid growth of BMI is correlated with the occurrence of depression in young individuals and may be a contributing factor to the development of depression in this demographic.

摘要

目的

近年来,年轻人患抑郁症的风险有所增加,儿童期体重指数(BMI)的变化可能是其发病的重要因素。然而,儿童期BMI变化与抑郁症风险之间的关系尚需进一步研究和探索。

方法

收集武汉市精神卫生中心医院体检中心的年度健康检查数据,共1226名学生。依次记录11岁、14岁和17岁学生的身高和体重,并在18岁时根据汉密尔顿抑郁量表(HAMD)对这些学生进行随访以评估抑郁情况。通过Logistic回归分析BMI变化趋势与抑郁之间的关系。

结果

BMI的增长趋势分为正常增长、增长缓慢和增长过快。与正常增长相比,增长缓慢组抑郁的比值比(OR)值为1.218(95%CI,0.995 - 1.493),差异无统计学意义(P = 0.056)。与正常增长相比,增长过快组抑郁的OR值为1.982(95%CI,1.243 - 3.177),差异有统计学意义(P = 0.003)。

结论

BMI的快速增长与年轻人抑郁症的发生相关,可能是该人群抑郁症发病的一个促成因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7113/11443293/8e15e3747582/ap-25-4-480_f001.jpg

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