Le Donne Andrea, Bodo Enrico
Chemistry Department, University of Rome "La Sapienza", Piazzale A. Moro 5, 00185 Rome, Italy.
Biophys Rev. 2021 Jan 14;13(1):147-160. doi: 10.1007/s12551-021-00782-0. eCollection 2021 Feb.
Boosted by the simplicity of their synthesis and low toxicity, cholinium and amino acid-based ionic liquids have attracted the attention of researchers in many different fields ranging from computational chemistry to electrochemistry and medicine. Among the uncountable IL variations, these substances occupy a space on their own due to their exceptional biocompatibility that stems from being entirely made by metabolic molecular components. These substances have undergone a rather intensive research activity because of the possibility of using them as greener replacements for traditional ionic liquids. We present here a short review in the attempt to provide a compendium of the state-of-the-art scientific research about this special class of ionic liquids based on the combination of amino acid anions and cholinium cations.
由于合成简单且毒性低,胆碱基和氨基酸基离子液体吸引了从计算化学到电化学和医学等许多不同领域研究人员的关注。在无数种离子液体变体中,这些物质因其特殊的生物相容性而独树一帜,这种生物相容性源于它们完全由代谢分子成分构成。由于有可能将它们用作传统离子液体的更环保替代品,这些物质已经经历了相当深入的研究活动。我们在此进行简短综述,试图提供一份关于这类基于氨基酸阴离子和胆碱阳离子组合的特殊离子液体的最新科学研究概要。