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本文引用的文献

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Loose ENDs: Electronic Nicotine Delivery Systems and the FDA's Recent Enforcement Policy.未解决的问题:电子尼古丁传送系统与美国食品药品监督管理局的近期执法政策
Eur Med J Respir. 2020 Nov;8(1):93-96.
2
Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air-liquid interface.亚微米气溶胶吸入增加了羰基化合物的水平,具有细胞毒性,并改变了暴露在气液界面的人支气管上皮细胞中的基因表达。
Respir Res. 2020 Nov 19;21(1):305. doi: 10.1186/s12931-020-01571-1.
3
Aerosol size distribution measurement of electronic cigarette emissions using combined differential mobility and inertial impaction methods: Smoking machine and puff topography influence.使用差分迁移率和惯性撞击组合方法测量电子烟排放物的气溶胶粒径分布:吸烟机和抽吸形貌的影响。
Aerosol Sci Technol. 2018;52(11):1233-1248. doi: 10.1080/02786826.2018.1513636. Epub 2018 Sep 14.
4
The JUUL E-Cigarette Elevates the Risk of Thrombosis and Potentiates Platelet Activation.JUUL 电子烟会增加血栓形成的风险,并增强血小板的激活。
J Cardiovasc Pharmacol Ther. 2020 Nov;25(6):578-586. doi: 10.1177/1074248420941681. Epub 2020 Jul 21.
5
Electronic Cigarette Use Among U.S. Adults, 2018.2018年美国成年人使用电子烟的情况
NCHS Data Brief. 2020 Apr(365):1-8.
6
Clinical Features of E-cigarette, or Vaping, Product Use-Associated Lung Injury in Teenagers.青少年使用电子烟或蒸气产品相关肺损伤的临床特征。
Pediatrics. 2020 Jul;146(1). doi: 10.1542/peds.2019-4104. Epub 2020 May 11.
7
Alterations in Vascular Function Associated With the Use of Combustible and Electronic Cigarettes.与可燃和电子烟使用相关的血管功能改变。
J Am Heart Assoc. 2020 May 5;9(9):e014570. doi: 10.1161/JAHA.119.014570. Epub 2020 Apr 29.
8
Nicotine in Senescence and Atherosclerosis.衰老与动脉粥样硬化中的尼古丁。
Cells. 2020 Apr 22;9(4):1035. doi: 10.3390/cells9041035.
9
Impaired lung function following e-cigarette or vaping product use associated lung injury in the first cohort of hospitalized adolescents.电子烟或雾化产品使用相关肺损伤后住院青少年的第一队列中肺功能受损。
Pediatr Pulmonol. 2020 Jul;55(7):1712-1718. doi: 10.1002/ppul.24787. Epub 2020 Apr 22.
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Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI).与电子烟或雾化产品使用相关的肺损伤(EVALI)中涉及的化学成分。
Toxics. 2020 Apr 3;8(2):25. doi: 10.3390/toxics8020025.

电子烟与心肺健康

E-Cigarettes and Cardiopulmonary Health.

机构信息

Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA.

Department of Medicine, Columbia University, New York, NY, USA.

出版信息

Function (Oxf). 2021 Feb 8;2(2):zqab004. doi: 10.1093/function/zqab004. eCollection 2021.

DOI:
10.1093/function/zqab004
PMID:33748758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7948134/
Abstract

E-cigarettes have surged in popularity over the last few years, particularly among youth and young adults. These battery-powered devices aerosolize e-liquids, comprised of propylene glycol and vegetable glycerin, typically with nicotine, flavors, and stabilizers/humectants. Although the use of combustible cigarettes is associated with several adverse health effects including multiple pulmonary and cardiovascular diseases, the effects of e-cigarettes on both short- and long-term health have only begun to be investigated. Given the recent increase in the popularity of e-cigarettes, there is an urgent need for studies to address their potential adverse health effects, particularly as many researchers have suggested that e-cigarettes may pose less of a health risk than traditional combustible cigarettes and should be used as nicotine replacements. This report is prepared for clinicians, researchers, and other health care providers to provide the current state of knowledge on how e-cigarette use might affect cardiopulmonary health, along with research gaps to be addressed in future studies.

摘要

电子烟在过去几年中越来越受欢迎,尤其是在年轻人和年轻人中。这些电池供电的设备将电子液体雾化,其中包含丙二醇和蔬菜甘油,通常还有尼古丁、香料和稳定剂/保湿剂。虽然使用可燃香烟与多种不良健康影响有关,包括多种肺部和心血管疾病,但电子烟对短期和长期健康的影响才刚刚开始研究。鉴于电子烟最近的普及程度有所增加,迫切需要进行研究来解决它们可能带来的健康影响,尤其是因为许多研究人员认为电子烟可能带来的健康风险比传统可燃香烟要小,应该被用作尼古丁替代品。本报告为临床医生、研究人员和其他医疗保健提供者编写,旨在提供有关电子烟使用如何影响心肺健康的最新知识,以及未来研究中需要解决的研究空白。