Markowicz Mateusz, Schötta Anna-Margarita, Höss Dieter, Kundi Michael, Schray Christina, Stockinger Hannes, Stanek Gerold
Emerg Infect Dis. 2021 Apr;27(4):1048-56. doi: 10.3201/eid2704.203366.
The aim of this prospective study was to assess the risk for tickborne infections after a tick bite. A total of 489 persons bitten by 1,295 ticks were assessed for occurrence of infections with sensu lato, , spp., spp., Neoehrlichia mikurensis, and relapsing fever borreliae. s.l. infection was found in 25 (5.1%) participants, of whom 15 had erythema migrans. Eleven (2.3%) participants were positive by PCR for N. mikurensis. One asymptomatic participant infected with was identified. Full engorgement of the tick (odds ratio 9.52) and confirmation of s.l. in the tick by PCR (odds ratio 4.39) increased the risk for infection. was highly abundant in ticks but not pathogenic to humans. Knowledge about the outcome of tick bites is crucial because infections with emerging pathogens might be underestimated because of limited laboratory facilities.
这项前瞻性研究的目的是评估蜱叮咬后蜱传感染的风险。对总共489名被1295只蜱叮咬的人进行了评估,以确定其是否感染狭义伯氏疏螺旋体、狭义埃立克体属、巴贝斯虫属、米库埃里希新埃立克体和回归热疏螺旋体。在25名(5.1%)参与者中发现了狭义伯氏疏螺旋体感染,其中15人出现游走性红斑。11名(2.3%)参与者米库埃里希新埃立克体PCR检测呈阳性。确定了一名感染狭义伯氏疏螺旋体的无症状参与者。蜱完全饱血(比值比9.52)以及通过PCR确认蜱中存在狭义伯氏疏螺旋体(比值比4.39)会增加感染风险。狭义伯氏疏螺旋体在蜱中高度常见,但对人类无致病性。了解蜱叮咬的后果至关重要,因为由于实验室设施有限,新出现病原体的感染可能被低估。