Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria.
Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria.
J Hosp Infect. 2021 May;111:47-49. doi: 10.1016/j.jhin.2021.03.011. Epub 2021 Mar 21.
We evaluated the bactericidal efficacy of two modified WHO-recommended alcohol-based hand rubs (3 mL) after a 15-s rubbing period using two different rub-in techniques (three vs six steps). The formulation based on 80% w/w ethanol and 0.5% v/v glycerol (modified WHO I) showed a mean log-reduction of 3.63 ± 0.87 (six steps) and 3.80 ± 0.71 (three steps) which was inferior to the reference treatment (4.27 ± 0.98; six steps). The efficacy of the formulation based on 75% w/w isopropanol and 0.5% v/v glycerol (modified WHO II) was not inferior to the reference treatment for either rub-in technique.
我们评估了两种改良后的世界卫生组织推荐的酒精基手部消毒剂（3 毫升）在 15 秒揉搓期后的杀菌效果，使用了两种不同的揉搓技术（三步和六步）。基于 80%w/w 乙醇和 0.5%v/v 甘油的配方（改良的世界卫生组织 I）显示出平均对数减少 3.63±0.87（六步）和 3.80±0.71（三步），低于参考治疗（六步）的 4.27±0.98。基于 75%w/w 异丙醇和 0.5%v/v 甘油的配方（改良的世界卫生组织 II）对于两种揉搓技术的效果均不低于参考治疗。
