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选择类固醇治疗骶髂关节注射治疗慢性下腰痛是否重要:一项回顾性研究。

Does Choice of Steroid Matter for Treatment of Chronic Low Back Pain with Sacroiliac Joint Injections: a Retrospective Study.

机构信息

Department of Anesthesia, Yale University School of Medicine, New Haven, CT, USA.

出版信息

Curr Pain Headache Rep. 2021 Mar 24;25(5):34. doi: 10.1007/s11916-021-00942-7.

Abstract

PURPOSE OF REVIEW

Prevalence of chronic low back pain (cLBP) is increasing. Sacroiliac joint (SIJ) is a common source of cLBP, but data behind its diagnosis and treatment is controversial. There is moderate quality evidence for effectiveness of therapeutic SIJ injections. However, there are no studies comparing the two most common steroid preparations, methylprednisolone (MTP) and triamcinolone (TAC) in SIJ injections.

RECENT FINDINGS

After institutional IRB approval, a retrospective chart review was conducted to evaluate the effectiveness of SIJ injections in terms of pain relief at 1-month follow-up and compare MTP versus TAC. All injections were performed by a single pain physician with fluoroscopic guidance.

RESULTS

Sixty-five percent of patients in the MTP group and 57% patients in the TAC group had >50% pain relief at 1-month follow-up, with no statistical difference between the two groups. Patients in the TAC group had significantly greater BMI and consisted of higher proportion of smokers (72% patients in TAC group versus 39% patients in the MTP group, p-value 0.004). Other sources of pain such as facet joints were unmasked post-procedurally after SIJ injections, with this unmasking being significant for the TAC group. Opiate use decreased in the MTP group from 35% pre-procedurally to 20% post-procedurally, and this difference did not reach statistical significance. Both MTP and TAC are effective in providing pain relief for SIJ pain at 1-month follow-up, with no statistical difference between the two types of steroids. Although not statistically significant, there is a modest reduction in opiate use in the MTP group.

摘要

目的综述

慢性下腰痛(cLBP)的患病率正在上升。骶髂关节(SIJ)是 cLBP 的常见来源,但关于其诊断和治疗的数据存在争议。有中等质量证据表明治疗性 SIJ 注射有效。然而,目前尚无研究比较 SIJ 注射中两种最常用的类固醇制剂,即甲泼尼龙(MTP)和曲安奈德(TAC)。

最新发现

在机构 IRB 批准后,进行了回顾性图表审查,以评估 SIJ 注射在 1 个月随访时缓解疼痛的效果,并比较 MTP 与 TAC。所有注射均由一名疼痛医师在透视引导下进行。

结果

MTP 组中有 65%的患者和 TAC 组中有 57%的患者在 1 个月随访时疼痛缓解>50%,两组之间无统计学差异。TAC 组患者的 BMI 明显更高,吸烟者比例也更高(TAC 组 72%的患者,而 MTP 组 39%的患者,p 值=0.004)。SIJ 注射后,其他来源的疼痛(如小关节)被揭示出来,TAC 组的这种揭示更为明显。MTP 组在术前有 35%的患者使用阿片类药物,术后降至 20%,但差异无统计学意义。MTP 和 TAC 均能有效缓解 1 个月随访时的 SIJ 疼痛,两种类固醇之间无统计学差异。虽然无统计学意义,但 MTP 组阿片类药物的使用量略有减少。

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