长期太空飞行后宇航员眼球持续扁平化
Persistent Globe Flattening in Astronauts following Long-Duration Spaceflight.
作者信息
Mader Thomas H, Gibson C Robert, Barratt Michael R, Miller Neil R, Subramanian Prem S, Killer Hanspeter E, Tarver William J, Sargsyan Ashot E, Garcia Kathleen, Hart Stephen F, Kramer Larry A, Riascos Roy, Brunstetter Tyson J, Lipsky William, Wostyn Peter, Lee Andrew G
机构信息
COL(R) US Army, Moab, Utah, USA.
Coastal Eye Associates, Webster, Texas, USA.
出版信息
Neuroophthalmology. 2020 Sep 3;45(1):29-35. doi: 10.1080/01658107.2020.1791189. eCollection 2021.
Abstract
Posterior globe flattening has been well-documented in astronauts both during and after long-duration space flight (LDSF) and has been observed as early as 10 days into a mission on the International Space Station. Globe flattening (GF) is thought to be caused by the disc centred anterior forces created by elevated volume and/or pressure within the optic nerve sheath (ONS). This might be the result of increased intracranial pressure, increased intraorbital ONS pressure from compartmentalisation or a combination of these mechanisms. We report posterior GF in three astronauts that has persisted for 7 years or more following their return from LDSFs suggesting that permanent scleral remodelling may have occurred.
摘要
后极部眼球扁平化在长期太空飞行期间及之后的宇航员中已有充分记录，早在国际空间站任务的第10天就已观察到。眼球扁平化（GF）被认为是由视神经鞘（ONS）内体积和/或压力升高所产生的以视盘为中心的向前作用力引起的。这可能是颅内压升高、因分隔导致眶内ONS压力增加或这些机制共同作用的结果。我们报告了三名宇航员出现后极部GF，在他们从长期太空飞行返回后这种情况持续了7年或更长时间，这表明可能发生了永久性巩膜重塑。
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