Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, Hainan Normal University, Haikou, Hainan, China.
Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, Hainan, China.
Nat Prod Res. 2022 Aug;36(15):3965-3971. doi: 10.1080/14786419.2021.1903002. Epub 2021 Mar 25.
Four unsaturated fatty acid derivatives including three new pantheric acids (), together with three known polyketides (), were isolated from a culture broth of the marine-derived fungus sp. SCAU150. Their complete structures were determined by NMR and HRESIMS data analyses. The antifungal activity of the isolated compounds above was evaluated and was found to show moderated activity toward the phytopathogenic fungus bio-80814 with an inhibition zone diameter of 6 mm under 5 µg/disc.
从海洋来源真菌 sp. SCAU150 的发酵液中分离得到了四种不饱和脂肪酸衍生物，包括三种新的 Pantheric 酸（）和三种已知的聚酮化合物（）。通过 NMR 和 HRESIMS 数据分析确定了它们的完整结构。对上述分离得到的化合物进行了抗真菌活性评价，发现化合物 对植物病原菌 bio-80814 具有中等活性，在 5μg/disc 下抑菌圈直径为 6mm。
