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新型 COST 行动——欧洲毒液网络(EUVEN):现代毒液学的协同作用和未来展望。

The new COST Action European Venom Network (EUVEN)-synergy and future perspectives of modern venomics.

机构信息

Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy.

Department of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 22, 2318 Hamar, Norway.

出版信息

Gigascience. 2021 Mar 25;10(3). doi: 10.1093/gigascience/giab019.

DOI:10.1093/gigascience/giab019
PMID:33764467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992391/
Abstract

Venom research is a highly multidisciplinary field that involves multiple subfields of biology, informatics, pharmacology, medicine, and other areas. These different research facets are often technologically challenging and pursued by different teams lacking connection with each other. This lack of coordination hampers the full development of venom investigation and applications. The COST Action CA19144-European Venom Network was recently launched to promote synergistic interactions among different stakeholders and foster venom research at the European level.

摘要

毒液研究是一个高度多学科的领域,涉及生物学、信息学、药理学、医学和其他领域的多个子领域。这些不同的研究方面通常在技术上具有挑战性,并且由缺乏相互联系的不同团队进行研究。这种缺乏协调阻碍了毒液研究和应用的全面发展。最近启动了 COST 行动 CA19144-欧洲毒液网络,以促进不同利益相关者之间的协同互动,并促进欧洲层面的毒液研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb72/7992391/f82c4ace017f/giab019fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb72/7992391/beec46ad30f3/giab019fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb72/7992391/f82c4ace017f/giab019fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb72/7992391/beec46ad30f3/giab019fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb72/7992391/f82c4ace017f/giab019fig2.jpg

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本文引用的文献

1
The Diversity of Venom: The Importance of Behavior and Venom System Morphology in Understanding Its Ecology and Evolution.毒液的多样性:理解毒液生态和进化的行为和毒液系统形态的重要性。
Toxins (Basel). 2019 Nov 14;11(11):666. doi: 10.3390/toxins11110666.
2
The Isolation of New Pore-Forming Toxins from the Sea Anemone Provides Insights into the Mechanisms of Actinoporin Evolution.从海葵中分离新型孔形成毒素,深入了解肌动蛋白孔形成蛋白进化的机制。
Toxins (Basel). 2019 Jul 10;11(7):401. doi: 10.3390/toxins11070401.
3
Potential Therapeutic Applications of Bee Venom on Skin Disease and Its Mechanisms: A Literature Review.
BMC Biol. 2023 Apr 13;21(1):82. doi: 10.1186/s12915-023-01581-7.
4
Modern venomics-Current insights, novel methods, and future perspectives in biological and applied animal venom research.现代毒液学——生物和应用动物毒液研究的当前见解、新方法和未来展望。
Gigascience. 2022 May 18;11. doi: 10.1093/gigascience/giac048.
5
Convergent evolution of venom gland transcriptomes across Metazoa.后生动物毒液腺转录组的趋同进化。
Proc Natl Acad Sci U S A. 2022 Jan 4;119(1). doi: 10.1073/pnas.2111392119.
6
Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations.利用精确的自由能计算预测可增强烟碱型乙酰胆碱受体作用效力和选择性的 Conotoxin 突变体。
Mar Drugs. 2021 Jun 25;19(7):367. doi: 10.3390/md19070367.
蜂毒在皮肤病中的潜在治疗应用及其机制:文献综述。
Toxins (Basel). 2019 Jun 27;11(7):374. doi: 10.3390/toxins11070374.
4
Venoms to the rescue.毒液来救援了。
Science. 2018 Aug 31;361(6405):842-844. doi: 10.1126/science.aau7761.
5
Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.通过烟碱型乙酰胆碱受体同源模型的对接和虚拟筛选发现肽配体。
Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E8100-E8109. doi: 10.1073/pnas.1703952114. Epub 2017 Sep 5.
6
Zebrafish (Danio rerio): A Potential Model for Toxinological Studies.斑马鱼(Danio rerio):毒理学研究的潜在模型。
Zebrafish. 2015 Oct;12(5):320-6. doi: 10.1089/zeb.2015.1102. Epub 2015 Jul 21.
7
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8
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Annu Rev Genomics Hum Genet. 2009;10:483-511. doi: 10.1146/annurev.genom.9.081307.164356.