CNC.IBILI-Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
CIBIT, Coimbra Institute for Biomedical Imaging and Translational Research, ICNAS - Institute of Nuclear Sciences Applied to Health, University of Coimbra, Coimbra, Portugal.
Autism. 2021 Aug;25(6):1746-1760. doi: 10.1177/13623613211002052. Epub 2021 Mar 25.
Neurofeedback is an emerging therapeutic approach in neuropsychiatric disorders. Its potential application in autism spectrum disorder remains to be tested. Here, we demonstrate the feasibility of real-time functional magnetic resonance imaging volitional neurofeedback in targeting social brain regions in autism spectrum disorder. In this clinical trial, autism spectrum disorder patients were enrolled in a program with five training sessions of neurofeedback. Participants were able to control their own brain activity in this social brain region, with positive clinical and neural effects. Larger, controlled, and blinded clinical studies will be required to confirm the benefits.
神经反馈是一种新兴的神经精神疾病治疗方法。其在自闭症谱系障碍中的潜在应用仍有待检验。在这里，我们展示了在自闭症谱系障碍中针对社交脑区进行实时功能磁共振成像自主神经反馈的可行性。在这项临床试验中，自闭症谱系障碍患者参加了一个包含五个神经反馈训练疗程的项目。参与者能够在这个社交脑区控制自己的大脑活动，并且具有积极的临床和神经效应。更大规模、对照和盲法的临床试验将是必要的，以确认其益处。
