Fiani Brian, Jarrah Ryan, Fiani Nicholas J, Runnels Juliana
Department of Neurosurgery, Desert Regional Medical Center, Palm Springs, California, United States.
College of Literature, Arts, and Sciences, University of Michigan, Flint, Michigan, United States.
Surg Neurol Int. 2021 Mar 2;12:79. doi: 10.25259/SNI_15_2021. eCollection 2021.
First characterized in the 19 century, spontaneous spinal epidural hematoma (SSEH) is known as the idiopathic accumulation of blood within the spinal canal's epidural space, causing symptoms varying from general back pain to complete paraplegia. With varying etiologies, a broad spectrum of severity and symptoms, a time-dependent resolution period, and no documented diagnosis or treatment algorithm, SSEH is a commonly misunderstood condition associated with increasing morbidity. While SSEH can occur at any vertebrae level, 16% of all SSEH cases occur in the cervical spine, making it a region of interest to clinicians.
Herein, the authors present two case examples describing the clinical presentation of SSEH, while also reviewing the literature to provide a comprehensive overview of its presentation, pathology, and treatment. The first case is a patient with nontraumatic sudden onset neck pain with rapidly progressing weakness. The second case is a patient with painless weakness that developed while taking 325 mg of aspirin daily.
Clinicians should keep SSEH in their differential diagnosis when seeing patients with nontraumatic sources of weakness in their extremities. The appropriate steps should be followed to diagnose and treat this condition with magnetic resonance imaging and surgical decompression if there are progressive neurological deficits. There is a continued need for more extensive database-driven studies to understand better SSEHs clinical presentation, etiology, and ultimate treatment.
自发性脊髓硬膜外血肿(SSEH)于19世纪首次被描述,是指椎管硬膜外间隙特发性血液积聚,可导致从一般性背痛到完全性截瘫等不同症状。由于病因各异、严重程度和症状范围广泛、有时间依赖性的消退期,且没有记录在案的诊断或治疗算法,SSEH是一种常被误解且发病率不断上升的疾病。虽然SSEH可发生于任何椎体水平,但所有SSEH病例中有16%发生在颈椎,这使其成为临床医生关注的区域。
在此,作者展示了两个描述SSEH临床表现的病例,同时回顾文献以全面概述其表现、病理和治疗。第一个病例是一名非创伤性突发颈部疼痛且伴有迅速进展性肌无力的患者。第二个病例是一名在每日服用325毫克阿司匹林时出现无痛性肌无力的患者。
临床医生在诊治四肢非创伤性肌无力患者时应将SSEH纳入鉴别诊断。如果存在进行性神经功能缺损,应采取适当步骤通过磁共振成像和手术减压来诊断和治疗该疾病。持续需要进行更广泛的基于数据库的研究,以更好地了解SSEH的临床表现、病因和最终治疗方法。