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对爱尔兰大流行第一波期间患者自我报告的 COVID-19 症状的分析。

An analysis of patient self-reported COVID-19 symptoms during the first wave of the pandemic in Ireland.

机构信息

School of Medicine, College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.

School of Mathematics, Statistics and Applied Mathematics, National University of Ireland, Galway, Ireland.

出版信息

Ir J Med Sci. 2022 Apr;191(2):543-546. doi: 10.1007/s11845-021-02598-z. Epub 2021 Mar 25.

Abstract

BACKGROUND

Since the outbreak of COVID-19 in December 2019, there have been more than 115 million cases worldwide (1). Symptoms of COVID-19 vary widely and the spectrum of clinical presentation has yet to be fully characterised (2). Many countries have detailed their early experience with COVID-19, with a focus on the clinical characteristics of the disease. However, to our knowledge, there has been no such study detailing symptoms in the Irish population.

AIM

Our aim is to describe COVID-19 symptoms in the Irish population at the beginning of the COVID-19 pandemic and compare symptoms between those reporting positive and negative test results.

METHOD

A Web page MyCovidSymptoms.ie was created by researchers at the National University of Ireland, Galway, in April 2020 to investigate COVID-19 symptoms in Ireland. The Web page invited participants to self-report RT-PCR test outcome data (positive, negative, untested), temperature and a range of symptoms (cough, shortness of breath, fatigue, loss of taste, loss of smell).

RESULTS

One hundred and twenty-three Irish participants who had a RT-PCR test for COVID-19 logged their symptoms. Eighty-four patients reported that they tested positive for COVID-19, and 39 patients reported a negative COVID-19 test. In our cohort of respondents with a positive COVID-19 test, 49/84 (58%) respondents reported a cough. Of the 39 respondents with a negative COVID-19 test, 17 (44%) reported having a cough. The distribution of temperature was similar in both those with and without COVID-19. Levels of self-reported fatigue were high in both groups with 65/84 (77%) of COVID-19-positive patients reporting fatigue and 30/39 (77%) of those who were COVID-19-negative reporting fatigue. New symptoms emerging at the time of data collection included loss of taste and smell. We demonstrated a higher proportion of loss of smell (p = 0.02) and taste (p = 0.01) in those reporting a positive result, compared to those reporting a negative result.

CONCLUSION

These data represents an early picture of the clinical characteristics of COVID-19 in an Irish population. It also highlights the potential use of self-reported data globally as a powerful tool in helping with the pandemic.

摘要

背景

自 2019 年 12 月 COVID-19 爆发以来,全球已有超过 1.15 亿例病例(1)。COVID-19 的症状差异很大,临床表现谱尚未完全描述(2)。许多国家详细描述了 COVID-19 的早期经验,重点是疾病的临床特征。然而,据我们所知,还没有这样的研究详细描述爱尔兰人群的症状。

目的

我们的目的是描述 COVID-19 在 COVID-19 大流行初期在爱尔兰人群中的症状,并比较检测结果呈阳性和阴性的人群之间的症状。

方法

2020 年 4 月,爱尔兰戈尔韦国立大学的研究人员创建了一个名为“MyCovidSymptoms.ie”的网页,以调查爱尔兰的 COVID-19 症状。该网页邀请参与者自行报告 RT-PCR 检测结果(阳性、阴性、未检测)、体温和一系列症状(咳嗽、呼吸急促、疲劳、味觉丧失、嗅觉丧失)。

结果

123 名接受 COVID-19 RT-PCR 检测的爱尔兰参与者记录了他们的症状。84 名患者报告 COVID-19 检测呈阳性,39 名患者报告 COVID-19 检测呈阴性。在我们的 COVID-19 检测呈阳性的患者队列中,49/84(58%)的患者报告有咳嗽。在 39 名 COVID-19 检测呈阴性的患者中,有 17 名(44%)报告有咳嗽。有 COVID-19 患者和无 COVID-19 患者的体温分布相似。两组患者的自我报告疲劳水平都很高,65/84(77%)的 COVID-19 阳性患者报告疲劳,30/39(77%)的 COVID-19 阴性患者报告疲劳。在数据收集时出现的新症状包括味觉和嗅觉丧失。我们发现,与报告阴性结果的患者相比,报告阳性结果的患者嗅觉丧失(p=0.02)和味觉丧失(p=0.01)的比例更高。

结论

这些数据代表了爱尔兰人群 COVID-19 临床特征的早期情况。它还强调了全球使用自我报告数据作为帮助应对大流行的有力工具的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/534b/7993982/f135c4ed5b61/11845_2021_2598_Fig1_HTML.jpg

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