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Chocolate and heartburn: evidence of increased esophageal acid exposure after chocolate ingestion.

作者信息

Murphy D W, Castell D O

机构信息

Department of Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.

出版信息

Am J Gastroenterol. 1988 Jun;83(6):633-6.

PMID:3376917
Abstract

Chocolate has been shown to decrease mean basal lower esophageal sphincter (LES) pressure, providing a rationale for the pathogenesis of chocolate-induced reflux symptoms. We assessed the relationship between chocolate ingestion and increased esophageal acid exposure using intraesophageal pH monitoring. Compared with ingestion of a dextrose control solution of similar volume, osmolality, and calories, postprandial ingestion of chocolate resulted in a significant increase in acid exposure in the first postprandial hour in patients with esophagitis. We conclude that this finding supports recommendations that patients with reflux esophagitis abstain from chocolate.

摘要

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