应用 10%和 30%葡萄糖酸内酯后皮肤水分的 Corneometric 评估。
Corneometric evaluation of skin moisture after application of 10% and 30% gluconolactone.
机构信息
Department of Cosmetology and Aesthetic Dermatology Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.
Department of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.
出版信息
Skin Res Technol. 2021 Sep;27(5):925-930. doi: 10.1111/srt.13044. Epub 2021 Mar 26.
BACKGROUND
Dry skin, caused by improper care or genetic conditions, can affect people of all ages. Skin hydration is determined its lipid content, which inhibits water loss from the epidermis, as well as other substances such as polyhydroxy acids and gluconolactone that can bind water. The aim of this study was to evaluate skin hydration after the application of 10% and 30% gluconolactone solution in a split face model.
MATERIALS AND METHODS
Sixteen healthy women were qualified for the study. Three split face treatments were performed, with 10% and 30% gluconolactone solution applied to two sides of the face. Skin moisture was measured before each treatment and a week after the last treatment at three measurement sites on either side of the face, that is, on the forehead, around the eye and on the cheek.
RESULTS
Corneometric measurements showed a significant increase in facial skin hydration after gluconolactone treatment. No significant differences were observed between the application of 10% and 30% solution.
CONCLUSION
Gluconolactone is a moisturizing substance which works well in dry skin care.
背景
皮肤干燥是由不当护理或遗传条件引起的，可影响所有年龄段的人群。皮肤水合作用取决于其脂质含量，脂质可以抑制表皮水分流失，以及其他物质如多元醇酸和葡萄糖酸内酯，这些物质可以结合水分。本研究的目的是评估 10%和 30%葡萄糖酸内酯溶液在分面模型中的应用后皮肤的水合作用。
材料与方法
共有 16 名健康女性符合研究条件。在面部的两侧分别进行了 3 次分面治疗，使用 10%和 30%的葡萄糖酸内酯溶液。在每次治疗前和最后一次治疗后的一周，在面部两侧的三个测量部位（额头、眼周和脸颊）测量皮肤水分。
结果
皮肤电导率测量显示，使用葡萄糖酸内酯后面部皮肤水合作用显著增加。应用 10%和 30%溶液之间没有观察到显著差异。
结论
葡萄糖酸内酯是一种保湿物质，在干性皮肤护理中效果良好。
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