MedStar Georgetown University Hospital, Washington, DC.
MedStar Georgetown University Hospital, Washington, DC.
Am J Kidney Dis. 2021 May;77(5):796-809. doi: 10.1053/j.ajkd.2020.11.024. Epub 2021 Mar 23.
Since maintenance hemodialysis (HD) first became available in the United States in 1962, there has been tremendous growth in the population of patients with kidney failure. HD has become a routine treatment carried out in outpatient clinics, hospitals, nursing facilities, and in patients' homes. Although it is a complex procedure, HD is quite safe. Serious complications are uncommon due to the use of modern HD machines and water treatment systems as well as the development of strict protocols to monitor various aspects of the HD treatment. The practicing nephrologist must be knowledgeable about life-threatening complications that can occur during HD and be able to recognize, manage, and prevent them. This installment in the AJKD Core Curriculum in Nephrology reviews the pathogenesis, management, and prevention of 9 HD emergencies. The HD emergencies covered include dialyzer reactions, dialysis disequilibrium syndrome, uremic/dialysis-associated pericarditis, air embolism, venous needle dislodgement, vascular access hemorrhage, hemolysis, dialysis water contamination, and arrhythmia episodes.
自 1962 年在美国首次开展维持性血液透析(HD)以来,肾衰竭患者的人数呈指数级增长。HD 已成为在门诊诊所、医院、护理机构和患者家中进行的常规治疗。尽管它是一个复杂的过程,但 HD 非常安全。由于使用现代 HD 机器和水处理系统以及制定了严格的监测 HD 治疗各个方面的方案,严重的并发症并不常见。执业肾病学家必须了解在 HD 过程中可能发生的危及生命的并发症,并能够识别、管理和预防这些并发症。本期 AJKD 肾脏病学核心课程回顾了 9 种 HD 急症的发病机制、处理和预防。涵盖的 HD 急症包括透析器反应、透析失衡综合征、尿毒症/透析相关心包炎、空气栓塞、静脉针移位、血管通路出血、溶血、透析用水污染和心律失常发作。