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妊娠期糖尿病女性抑郁和焦虑症状的患病率:一项纵向队列研究。

Prevalence of depressive and anxiety symptoms in women with gestational diabetes: a longitudinal cohort study.

机构信息

Department of Psychology, Faculty of Arts, University of Ljubljana, Ljubljana, Slovenia.

University Medical Center Ljubljana, Zaloška 2, 1000, Ljubljana, Slovenia.

出版信息

Acta Diabetol. 2021 Aug;58(8):1091-1100. doi: 10.1007/s00592-021-01706-w. Epub 2021 Mar 26.

Abstract

AIMS

Prevalence of mental disorders in women with gestational diabetes mellitus (GDM) is not well defined; however, their presence could interfere with effective glucose self-management. Therefore, we aimed to assess the incidence of depression and anxiety symptoms in women with GDM in the 2nd and 3rd trimester of pregnancy and their impact on glycemic control.

METHODS

We included consecutive women undergoing the GDM screening test at the University Medical Centre Ljubljana. Women with GDM (n = 77) and women without GDM (n = 103) completed questionnaires on depression and anxiety symptomatology, health locus of control and social support.

RESULTS

The incidence of depression symptoms in the 2nd trimester is higher in women with GDM (23.4%) than in women without GDM (10.7%; p = 0.022; OR = 2.6). The incidence of depression and anxiety symptomatology did not change significantly from 2nd to 3rd trimester within both groups; however, an increase in the average severity of depression symptomatology was observed. Glycemic control was negatively associated with the external health locus of control.

CONCLUSIONS

Our results highlight the need for depression screening early on during pregnancy, especially in women with GDM. Timely psychological support may contribute to better GDM management and possibly prevent negative pregnancy outcomes.

摘要

目的

妊娠期糖尿病(GDM)女性的精神障碍患病率尚未明确,但这些障碍的存在可能会影响有效的血糖自我管理。因此,我们旨在评估 GDM 女性在妊娠第 2 至 3 期出现抑郁和焦虑症状的发生率及其对血糖控制的影响。

方法

我们纳入了卢布尔雅那大学医学中心进行 GDM 筛查的连续女性患者。GDM 女性(n=77)和非 GDM 女性(n=103)完成了抑郁和焦虑症状、健康控制源和社会支持的问卷。

结果

GDM 女性(23.4%)第 2 期抑郁症状的发生率高于非 GDM 女性(10.7%;p=0.022;OR=2.6)。两组的抑郁和焦虑症状发生率从第 2 期到第 3 期均无显著变化;然而,抑郁症状的平均严重程度有所增加。血糖控制与外部健康控制源呈负相关。

结论

我们的结果强调了在妊娠早期对抑郁进行筛查的必要性,尤其是在 GDM 女性中。及时的心理支持可能有助于更好地管理 GDM,并可能预防不良妊娠结局。

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