Department of Stomatology, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, P.R. China.
Bioconjug Chem. 2021 Apr 21;32(4):627-638. doi: 10.1021/acs.bioconjchem.1c00129. Epub 2021 Mar 29.
As dental implants have become one of the main treatment options for patients with tooth loss, the number of patients with peri-implant diseases has increased. Similar to periodontal diseases, peri-implant diseases have been associated with dental plaque formation on implants. Unconventional approaches have been reported to remove plaque from infected implants, but none of these methods can completely and permanently solve the problem of bacterial invasion. Fortunately, the constant development of antibacterial implant materials is a promising solution to this situation. In this review, the development and study of different antibacterial strategies for dental implant materials for the prevention of peri-implantitis are summarized. We hope that by highlighting the advantages and limitations of these antimicrobial strategies, we can assist in the continued development of oral implant materials.
随着种植牙已成为治疗牙齿缺失患者的主要手段之一，患有种植体周围病的患者数量也在增加。与牙周病类似，种植体周围病与种植体上牙菌斑的形成有关。据报道，有一些非传统方法可用于清除受感染种植体上的菌斑，但这些方法都不能完全和永久地解决细菌入侵的问题。幸运的是，抗菌种植材料的不断发展为解决这一问题提供了有希望的解决方案。在这篇综述中，总结了不同抗菌策略在预防种植体周围炎方面对牙科种植材料的开发和研究。我们希望通过突出这些抗菌策略的优点和局限性，能有助于口腔种植材料的不断发展。
