Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC, USA; Medical Research Service, Durham Veterans Administration Medical Center, Durham, NC, USA.
Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC, USA.
Rheum Dis Clin North Am. 2021 May;47(2):215-228. doi: 10.1016/j.rdc.2020.12.004. Epub 2021 Feb 25.
Systemic lupus erythematous is a systemic autoimmune disease that can cause severe pain and impair quality of life. Pain in lupus can arise from a variety of mechanisms and is usually assessed in terms of activity and damage. In contrast, categorization of symptoms as type 1 and type 2 manifestations encompasses a broader array of symptoms, including widespread pain, fatigue, and depression that may track together. The categorization of symptoms as type 1 and type 2 manifestations can facilitate communication between patient and provider as well as provide a framework to address more fully the complex symptoms experienced by patients.
系统性红斑狼疮是一种全身性自身免疫性疾病，可导致严重疼痛并降低生活质量。狼疮引起的疼痛可能源于多种机制，通常根据活动度和损伤程度进行评估。相比之下，将症状归类为 1 型和 2 型表现则涵盖了更广泛的症状，包括广泛的疼痛、疲劳和抑郁，这些症状可能会同时出现。将症状归类为 1 型和 2 型表现有助于患者和提供者之间的沟通，并为更全面地解决患者所经历的复杂症状提供框架。
