School of Nursing and Midwifery Amol, Mazandaran University of Medical Sciences, Sari, Iran.
College of Nursing, Michigan State University, East Lansing, MI, USA.
Support Care Cancer. 2021 Oct;29(10):6013-6019. doi: 10.1007/s00520-021-06172-2. Epub 2021 Mar 29.
Maintenance of quality of life (QOL) is vital for adaptation to life-threatening and chronic illnesses such as cancer. Therefore, the evaluation and strengthening of personal psychological resources that support QOL for patients with cancer is paramount. This study investigated the potential mediating role of hope in the relationship between spiritual well-being and QOL in Iranian cancer patients.
A correlational predictive design was used with 200 patients with varying types and stage of cancer. Demographic and health characteristic surveys, spiritual well-being (SWB), adult hope, and EORTC QLQ-c30 scales were used for measuring the study constructs. Path analysis modeling was used to determine mediation relationships.
Patients' QOL was affected by SWB and hope. Religious (β = 0.205, p = 0.002) and existential (β = 0.286, p < 0.001) SWB dimensions and hope (β = 0.263, p < 0.001) improved QOL scores. The presence of hope partially mediated the relationship between SWB and QOL.
Quality of life was directly affected by SWB and was further improved by the presence of hope. The study suggests that maintenance of hope is essential to QOL in Iranian patients with cancer.
维持生活质量（QOL）对于适应危及生命和慢性疾病（如癌症）至关重要。因此，评估和加强支持癌症患者 QOL 的个人心理资源至关重要。本研究调查了希望在伊朗癌症患者的精神幸福感与 QOL 之间的关系中的潜在中介作用。
采用相关性预测设计，对 200 名患有不同类型和阶段癌症的患者进行研究。使用人口统计学和健康特征调查、精神幸福感（SWB）、成人希望和 EORTC QLQ-c30 量表来测量研究结构。路径分析模型用于确定中介关系。
患者的 QOL 受到 SWB 和希望的影响。宗教（β=0.205，p=0.002）和存在（β=0.286，p<0.001）SWB 维度以及希望（β=0.263，p<0.001）改善了 QOL 评分。希望的存在部分中介了 SWB 与 QOL 之间的关系。
QOL 直接受到 SWB 的影响，并通过希望的存在得到进一步改善。研究表明，在伊朗癌症患者中，维持希望对于 QOL 至关重要。
