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听力损失、耳鸣和高血压:巴西成人健康纵向研究(ELSA-Brasil)的基线数据分析。

Hearing loss, tinnitus, and hypertension: analysis of the baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

机构信息

Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina (FMUSP), Universidade de Sao Paulo, Sao Paulo, SP, BR.

Centro de Pesquisa Clinica e Epidemiologica, Hospital Universitario, Universidade de Sao Paulo, Sao Paulo, SP, BR.

出版信息

Clinics (Sao Paulo). 2021 Mar 26;76:e2370. doi: 10.6061/clinics/2021/e2370. eCollection 2021.

DOI:10.6061/clinics/2021/e2370
PMID:33787654
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7978663/
Abstract

OBJECTIVES

To investigate the association among hypertension, tinnitus, and sensorineural hearing loss and evaluate the influence of other covariates on this association.

METHODS

Baseline data (2008-2010) from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) were analyzed. Altogether, 900 participants were evaluated. The baseline assessment consisted of a 7-hour examination to obtain clinical and laboratory variables. Hearing was measured using pure-tone audiometry.

RESULTS

Overall, 33.3% of the participants had hypertension. Participants with hypertension were more likely to be older, male, and diabetic compared to those without hypertension. The prevalence of tinnitus was higher among hypertensive participants and the odds ratio for tinnitus was higher in participants with hypertension than in those without hypertension. However, the difference was not significant after adjusting for age. Audiometric results at 250-8,000 Hz were worse in participants with hypertension than in those without hypertension in the crude analysis; however, the differences were not significant after adjustment for age, sex, diagnosis of diabetes, and exposure to noise. No significant difference was observed in hearing thresholds among participants having hypertension for <6 years, those having hypertension for ≥6 years, and individuals without hypertension.

CONCLUSION

Hearing thresholds were worse in participants with hypertension. However, after adjusting for age, sex, diagnosis of diabetes, and exposure to noise, no significant differences were observed between participants with and without hypertension. A higher prevalence of tinnitus was observed in participants with hypertension compared to those without hypertension, but without significance after adjusting for age.

摘要

目的

探讨高血压、耳鸣与感音神经性听力损失之间的关联,并评估其他协变量对这种关联的影响。

方法

对巴西成人健康纵向研究(ELSA-Brasil)的基线数据(2008-2010 年)进行分析。共评估了 900 名参与者。基线评估包括 7 小时的检查,以获取临床和实验室变量。使用纯音测听法测量听力。

结果

总体而言,33.3%的参与者患有高血压。与无高血压者相比,高血压患者更可能年龄较大、为男性且患有糖尿病。高血压患者耳鸣的患病率较高,且高血压患者耳鸣的比值比高于无高血压者。然而,调整年龄后差异无统计学意义。未经年龄调整的分析中,高血压患者在 250-8000 Hz 的听力结果更差;然而,调整年龄、性别、糖尿病诊断和噪声暴露后,差异无统计学意义。在高血压<6 年、高血压≥6 年和无高血压的参与者中,听力阈值没有显著差异。

结论

高血压患者的听力阈值较差。然而,调整年龄、性别、糖尿病诊断和噪声暴露后,高血压患者和无高血压患者之间没有观察到显著差异。与无高血压者相比,高血压患者耳鸣的患病率更高,但调整年龄后无统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7588/7978663/941ede66bf3e/cln-76-e2370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7588/7978663/941ede66bf3e/cln-76-e2370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7588/7978663/941ede66bf3e/cln-76-e2370-g001.jpg

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