用于急性鼻窦炎鼻腔冲洗的带鼻用涂抹器注射器与单用注射器的比较：一项配对随机对照试验
Syringe with Nasal Applicator versus Syringe Alone for Nasal Irrigation in Acute Rhinosinusitis: A Matched-Pair Randomized Controlled Trial.
作者信息
Piromchai Patorn, Phannikul Chayakorn, Thanaviratananich Sanguansak
机构信息
Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
出版信息
Biomed Hub. 2021 Jan 27;6(1):25-29. doi: 10.1159/000512664. eCollection 2021 Jan-Apr.
BACKGROUND/AIMS: Nasal saline irrigation is a common procedure to relieve nasal symptoms in upper respiratory tract diseases. There is no consensus on the recommended nasal saline delivery devices. The objectives of this study were to evaluate efficacy, satisfaction, adherence, and adverse effects in patients with acute upper respiratory tract diseases using a syringe with a nasal applicator for nasal irrigation.
METHODS
Patients with acute nasopharyngitis, acute rhinitis, or acute rhinosinusitis were randomly allocated to use either (1) a syringe with a nasal applicator or (2) a syringe alone to irrigate one nostril. After the patients had completed irrigation with the allocated device in one nostril, they were instructed to perform nasal irrigation using the other device in the other nostril. All patients were instructed to use a syringe with a nasal applicator at home. The efficacy, satisfaction scores, adherence, and adverse effects were recorded.
RESULTS
Sixty-four patients were enrolled. The mean age of the patients was 33.95 years (18-59 years). The mean duration of symptoms was 4.80 days. None of the enrolled patients regularly performed nasal irrigation. Forty-two had acute nasopharyngitis, 10 had acute rhinitis, and 12 had acute rhinosinusitis. At baseline, the mean overall efficacy score for the syringe with a nasal applicator was 8.17 ± 1.43, and that for the syringe alone was 5.95 ± 2.02 (MD 2.23, < 0.001, 95% CI 1.75-2.70). At 1 week, the syringe with the nasal applicator had significantly higher scores in 3 of 4 domains, including symptom relief, ease of use, and patients' willingness to recommend the device to others, compared to baseline ( < 0.05). None of the enrolled patients had epistaxis, retained/dislodged the applicator during irrigation, or experienced an allergic reaction to the applicator after 1 week of nasal irrigation.
CONCLUSION
Use of a syringe with an applicator for nasal irrigation yielded high scores in overall efficacy.
背景/目的：鼻腔盐水冲洗是缓解上呼吸道疾病鼻腔症状的常用方法。对于推荐使用的鼻腔盐水输送装置尚无共识。本研究的目的是评估使用带有鼻腔喷头的注射器进行鼻腔冲洗的急性上呼吸道疾病患者的疗效、满意度、依从性和不良反应。
方法
患有急性鼻咽炎、急性鼻炎或急性鼻窦炎的患者被随机分配使用（1）带有鼻腔喷头的注射器或（2）单独的注射器冲洗一侧鼻孔。患者使用分配的装置冲洗一侧鼻孔后，被指示使用另一种装置冲洗另一侧鼻孔。所有患者均被指示在家中使用带有鼻腔喷头的注射器。记录疗效、满意度评分、依从性和不良反应。
结果
共纳入64例患者。患者的平均年龄为33.95岁（18 - 59岁）。症状的平均持续时间为4.80天。所有纳入患者均未定期进行鼻腔冲洗。42例患有急性鼻咽炎，10例患有急性鼻炎，12例患有急性鼻窦炎。基线时，带有鼻腔喷头的注射器的平均总体疗效评分为8.17±1.43，单独注射器的评分为5.95±2.02（MD 2.23，<0.001，95%CI 1.75 - 2.70）。在第1周时，与基线相比（<0.05），带有鼻腔喷头的注射器在4个领域中的3个领域得分显著更高，包括症状缓解、易用性和患者向他人推荐该装置的意愿。在鼻腔冲洗1周后，所有纳入患者均未出现鼻出血、冲洗过程中喷头滞留/脱落或对喷头过敏反应。
结论
使用带有喷头的注射器进行鼻腔冲洗在总体疗效上得分较高。
Zotero 插件