Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Biomed Res Int. 2021 Mar 18;2021:6631856. doi: 10.1155/2021/6631856. eCollection 2021.
Oral submucous fibrosis (OSMF) is a kind of chronic, insidious disease, and it is categorized into potentially malignant disorders (PMD), which poses a global and regional problem to public health. It is considered to be a multifactorial disease, such as due to areca nut chewing, trace element disorders, and genetic susceptibility. However, there is still no unanimous conclusion on its pathogenesis, diagnosis, and treatment strategies. Hence, this article provides a comprehensive review and prospect of OSMF research, providing scholars and clinicians with a better perspective and new ideas for the research and treatment of OSMF.
口腔黏膜下纤维性变(OSMF)是一种慢性、隐匿性疾病,被归类为潜在恶性疾病(PMD),对全球和地区的公共健康构成威胁。它被认为是一种多因素疾病,如因咀嚼槟榔、微量元素紊乱和遗传易感性等因素导致。然而,其发病机制、诊断和治疗策略仍没有统一的结论。因此,本文对 OSMF 的研究进行了全面的回顾和展望,为学者和临床医生提供了更好的视角和新的思路,以促进 OSMF 的研究和治疗。