van Alphen W A, Smith A R, ten Kate F J
Department of Surgery, University Hospital Rotterdam, Dijkzigt, The Netherlands.
J Hand Surg Am. 1988 May;13(3):415-22. doi: 10.1016/s0363-5023(88)80022-4.
Excision and replantation of the latissimus dorsi muscle of the rabbit was done after various periods of hypothermic ischemia (5 degrees C). Sections studied under the light microscope were classified as having minimal changes, slight degenerative changes, severe degenerative changes, or necrosis. In all sections of the 24-hour group total or nearly total necrosis was found. In the 5-, 8-, and 16-hour groups slight degenerative changes and severe degenerative changes, with a severe reactive proliferation of fibroblasts were seen. A sliding scale was found in which severe degenerative changes were seen more often as ischemia time lasted longer. No statistical significance was found between the various groups.
在不同时长的低温缺血（5摄氏度）后，对兔子的背阔肌进行切除并再植。在光学显微镜下研究的切片被分类为具有最小变化、轻微退行性变化、严重退行性变化或坏死。在24小时组的所有切片中均发现完全或几乎完全坏死。在5小时、8小时和16小时组中，可见轻微退行性变化和严重退行性变化，伴有成纤维细胞的严重反应性增殖。发现了一种渐变关系，即随着缺血时间延长，严重退行性变化更常出现。各小组之间未发现统计学意义。
