School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun, 130022, China.
Center for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
J Nanobiotechnology. 2021 Apr 1;19(1):96. doi: 10.1186/s12951-021-00825-4.
The development of two-dimensional (2D) monoelemental nanomaterials (Xenes) for biomedical applications has generated intensive interest over these years. In this paper, the biomedical applications using Xene-based 2D nanomaterials formed by group VA (e.g., BP, As, Sb, Bi) and VIA (e.g., Se, Te) are elaborated. These 2D Xene-based theranostic nanoplatforms confer some advantages over conventional nanoparticle-based systems, including better photothermal conversion, excellent electrical conductivity, and large surface area. Their versatile and remarkable features allow their implementation for bioimaging and theranostic purposes. This concise review is focused on the current developments in 2D Xenes formed by Group VA and VIA, covering the synthetic methods and various biomedical applications. Lastly, the challenges and future perspectives of 2D Xenes are provided to help us better exploit their excellent performance and use them in practice.
二维(2D)单元素纳米材料(Xenes)在生物医学应用方面的发展近年来引起了广泛关注。本文详细阐述了基于 V 族 A (如 BP、As、Sb、Bi)和 VIA (如 Se、Te)的二维 Xenes 纳米材料的生物医学应用。与传统的基于纳米粒子的系统相比,这些基于二维 Xenes 的治疗诊断纳米平台具有一些优势,包括更好的光热转换、优异的导电性和较大的表面积。它们的多功能性和显著特性使其可用于生物成像和治疗诊断目的。本综述重点介绍了由 V 族 A 和 VIA 组成的二维 Xenes 的最新发展,涵盖了合成方法和各种生物医学应用。最后,提供了二维 Xenes 面临的挑战和未来展望,以帮助我们更好地利用它们的优异性能并将其应用于实际中。
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