Research Center for Green Printing Nanophotonic Materials, Jiangsu Key Laboratory for Environmental Functional Materials, School of Chemistry, Biology and Materials Engineering, Suzhou University of Science and Technology, Suzhou, 215009, China.
Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Adv Healthc Mater. 2018 Apr;7(8):e1701158. doi: 10.1002/adhm.201701158. Epub 2017 Dec 27.
MoS nanosheets, a typical kind of layered transition metal dichalcogenides with the 2D structure and many unique physical and chemical properties, have attracted a lot of research interests in various fields. Typically, MoS nanosheets present similarities to graphene in terms of their large surface area and strong absorbance in near-infrared region, which in combination with their easily functionalized surface make them promising nanoplatforms in biomedical applications. Herein, the progress of MoS nanosheets and their composites in the area of nanomedicine, with the emphasis on their synthesis and modification strategies, their biomedical applications in biosensing, imaging and therapy, as well as evaluations of their in vivo behaviors and toxicology profiles are summarized. Finally, the challenges and opportunities of applying MoS -based nanomaterials in the biomedicine areas will be discussed.
二硫化钼纳米片是一种典型的二维层状过渡金属二硫化物，具有许多独特的物理和化学性质，在各个领域引起了广泛的研究兴趣。通常，二硫化钼纳米片在大表面积和近红外区域的强吸收率方面与石墨烯相似，加上其易于功能化的表面，使它们成为生物医学应用中有前途的纳米平台。本文综述了二硫化钼纳米片及其复合材料在纳米医学领域的研究进展，重点介绍了它们的合成和修饰策略、在生物传感、成像和治疗中的生物医学应用，以及它们在体内行为和毒理学特征的评价。最后，讨论了应用基于二硫化钼的纳米材料在生物医学领域的挑战和机遇。
