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一名儿科患者出现腹痛和脾肿大的罕见病例。

An unusual case of abdominal pain and splenomegaly in a paediatric patient.

作者信息

Eckbo Eric J, Mijovic Hana, Tam Jennifer, Goldfarb David M, Kollmann Tobias R

机构信息

Division of Medical Microbiology & Infection Control, Department of Pathology & Laboratory Medicine, Vancouver General Hospital, Vancouver, BC, Canada.

Division of Pediatric Infectious Diseases, Department of Pediatrics, British Columbia Children's Hospital, Vancouver, BC, Canada.

出版信息

SAGE Open Med Case Rep. 2021 Feb 1;9:2050313X21991059. doi: 10.1177/2050313X21991059. eCollection 2021.

Abstract

species are members of the oral microbiota and have been found to cause a wide spectrum of opportunistic infections. We describe the case of a previously healthy teenager with a large splenic abscess secondary to , successfully managed with percutaneous drainage and intravenous antibiotics. Identification of the organism was achieved using anaerobic culture of the aspirated fluid and matrix-assisted laser desorption/ionization time of flight, later confirmed by 16S ribosomal RNA metagenomic sequencing of the fluid. are typically associated with oropharyngeal infections but are very rarely implicated in splenic abscesses. Aerobic and anaerobic blood cultures should be drawn when an intra-abdominal infection is suspected in a paediatric patient, and empiric antimicrobial therapy should be administered with coverage for gram-positive, gram-negative, and anaerobic bacteria.

摘要

这些菌种是口腔微生物群的成员,已被发现可引起广泛的机会性感染。我们描述了一例先前健康的青少年病例,该患者继发巨大脾脓肿,通过经皮引流和静脉使用抗生素成功治疗。通过对吸出液进行厌氧培养和基质辅助激光解吸/电离飞行时间质谱鉴定出该病原体,随后通过对液体进行16S核糖体RNA宏基因组测序得到证实。这些菌种通常与口咽感染有关,但极少与脾脓肿有关。当怀疑儿科患者有腹腔内感染时,应进行需氧和厌氧血培养,并应给予覆盖革兰氏阳性菌、革兰氏阴性菌和厌氧菌的经验性抗菌治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7db0/7970672/8a0b432198b4/10.1177_2050313X21991059-fig1.jpg

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