Kunadia Anuj, Leong Michael B, Komanduri Karthikram, Abdelmasih Randa, Tarasiuk-Rusek Aneta
Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.
Internal Medicine, University of Central Florida, Orlando, USA.
Cureus. 2021 Jun 15;13(6):e15660. doi: 10.7759/cureus.15660. eCollection 2021 Jun.
may be implicated in cases of emphysematous cholecystitis (EC) and carries a high mortality risk, especially in individuals with heart disease, renal insufficiency, and underlying malignancy. infections are rarely detected in the setting of cholecystitis possibly due to the difficulty with properly culturing the bacteria. We describe a case of a patient with EC in whom blood cultures were positive for growth of in one of two samples. The patient was treated with empiric antibiotic therapy consisting of metronidazole and cefepime. In patients with EC and negative cultures, it is possible that they may have an undetected infection with fusobacteria, which carries a high mortality risk. As such, clinicians should maintain a high degree of suspicion of obligate anaerobic infection in patients who have negative blood culture for growth in the setting of EC and consider continuation of adequate antimicrobial coverage.
可能与气肿性胆囊炎（EC）病例有关，且具有高死亡风险，尤其是在患有心脏病、肾功能不全和潜在恶性肿瘤的个体中。在胆囊炎的情况下，感染很少被检测到，这可能是由于正确培养细菌存在困难。我们描述了一例EC患者，其两份血培养样本中有一份检测到[细菌名称未给出]生长呈阳性。该患者接受了由甲硝唑和头孢吡肟组成的经验性抗生素治疗。对于EC且培养结果为阴性的患者，有可能存在未被检测到的梭杆菌感染，这种感染具有高死亡风险。因此，临床医生对于在EC情况下血培养无生长的患者应高度怀疑存在专性厌氧菌感染，并考虑继续给予充分的抗菌覆盖。
