在卵巢储备功能下降和/或与年龄相关的生育能力下降的患者中进行卵母细胞冷冻保存后的决策后悔及其相关因素。
Decision regret and associated factors following oocyte cryopreservation in patients with diminished ovarian reserve and/or age-related fertility decline.
机构信息
Women's Health Center, Assisted Reproduction Unit, American Hospital, Guzelbahce Sokak, No: 20 Nisantasi, 34365, Istanbul, Turkey.
Fulya IVF Center, Bahçeci Health Group, 34394, Istanbul, Turkey.
出版信息
J Assist Reprod Genet. 2021 Jun;38(6):1469-1479. doi: 10.1007/s10815-021-02164-7. Epub 2021 Apr 2.
PURPOSE
To evaluate the prevalence and factors associated with decision regret following oocyte cryopreservation (OC) in women with diminished ovarian reserve (DOR) and/or age-related fertility decline (ARFD).
METHODS
A cross-sectional survey study was conducted to five hundred fifty-two women with DOR and/or ARFD who underwent OC between 2014 and 2019 in two private-assisted reproductive units in Istanbul, Turkey. Decision regret was measured using the validated Decision Regret Scale (DRS).
RESULTS
The median and mean DRS scores were 10 (interquartile range: 25) and 13.4 (SD: 13.2, range 0-70), respectively. Eighty-five (52.5%) women reported mild regret and 26 (16%) had moderate to severe regret. Decision regret was inversely associated with the belief in fate regarding childbearing and trust in the efficacy of OC.
CONCLUSIONS
The prevalence of severe decision regret among patients with DOR and/or ARFD undergoing OC is low. Women who had belief in fate and trusted in the efficacy of oocyte cryopreservation had significantly lower decisional regret.
目的
评估在卵巢储备功能减退（DOR）和/或与年龄相关的生育力下降（ARFD）的女性中进行卵母细胞冷冻保存（OC）后决策后悔的发生率及相关因素。
方法
本研究为一项横断面调查研究，纳入了 2014 年至 2019 年在土耳其伊斯坦布尔的两家私立辅助生殖机构接受 OC 的 552 名 DOR 和/或 ARFD 女性。采用经过验证的决策后悔量表（DRS）来衡量决策后悔。
结果
DRS 的中位数和平均值分别为 10（四分位距：25）和 13.4（标准差：13.2，范围 0-70）。85 名（52.5%）女性报告轻度后悔，26 名（16%）报告中度至重度后悔。决策后悔与对生育的命运信念以及对 OC 疗效的信任呈负相关。
结论
在接受 OC 的 DOR 和/或 ARFD 患者中，严重决策后悔的发生率较低。相信命运和信任卵母细胞冷冻保存疗效的女性决策后悔明显较低。
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