Glosz Karolina, Stolarczyk Agnieszka, Jarosz Tomasz
Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland.
Materials (Basel). 2021 Mar 11;14(6):1369. doi: 10.3390/ma14061369.
Conjugated polymers are widely used in the development of sensors, but even though they are sensitive and robust, they typically show limited selectivity, being cross-sensitive to many substances. In turn, molecular imprinting is a method involving modification of the microstructure of the surface to incorporate cavities, whose shape matches that of the "template"-the analyte to be detected, resulting in high selectivity. The primary goal of this review is to report on and briefly explain the most relevant recent developments related to sensors utilising molecularly imprinted polypyrrole layers and their applications, particularly regarding the detection of bioactive substances. The key approaches to depositing such layers and the most relevant types of analytes are highlighted, and the various trends in the development of this type of sensors are explored.
共轭聚合物在传感器开发中被广泛应用,然而,尽管它们灵敏且耐用,但通常选择性有限,对许多物质存在交叉敏感性。反过来,分子印迹是一种涉及对表面微观结构进行修饰以纳入腔体的方法,这些腔体的形状与“模板”(即待检测的分析物)相匹配,从而实现高选择性。本综述的主要目的是报告并简要解释与利用分子印迹聚吡咯层的传感器及其应用相关的最新重要进展,特别是关于生物活性物质的检测。重点介绍了沉积此类层的关键方法以及最相关的分析物类型,并探讨了这类传感器发展的各种趋势。