Arnal-Gómez Anna, Cebrià I Iranzo Maria A, Tomas Jose M, Tortosa-Chuliá Maria A, Balasch-Bernat Mercè, Sentandreu-Mañó Trinidad, Forcano Silvia, Cezón-Serrano Natalia
Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain.
Research Unit in Clinical Biomechanics (UBIC), University of Valencia, 46010 Valencia, Spain.
J Clin Med. 2021 Mar 2;10(5):1018. doi: 10.3390/jcm10051018.
Recently the European Working Group on Sarcopenia in Older People (EWGSOP2) has updated diagnostic criteria for sarcopenia, which consist of one or more measures of muscle strength, muscle mass, and physical performance, plus an initial screening test called SARC-F. The main objective was to compare the number of cases of sarcopenia, using the different measurements and screening options. A cross-sectional study was conducted on Spanish older adults ( = 272, 72% women). Combining the different measures proposed by the steps described in the EWGSOP2 algorithm, 12 options were obtained (A-L). These options were studied in each of the three models: (1) using SARC-F as initial screening; (2) not using SARC-F; and (3) using SARC-CalF instead of SARC-F. A χ independence test was statistically significant (χ(6) = 88.41, < 0.001), and the association between the algorithm used and the classification of sarcopenia was moderate (Cramer's V = 0.226). We conclude that the different EWGSOP2 measurement options imply case-finding differences in the studied population. Moreover, when applying the SARC-F, the number of people classified as sarcopenic decreases. Finally, when SARC-CalF is used as screening, case finding of sarcopenic people decreases. Thus, clinical settings should consider these outcomes, since these steps can make preventive and therapeutic interventions on sarcopenia vary widely.
最近,欧洲老年人肌肉减少症工作组(EWGSOP2)更新了肌肉减少症的诊断标准,该标准由肌肉力量、肌肉质量和身体表现的一项或多项测量指标,以及一项名为SARC-F的初始筛查测试组成。主要目的是比较使用不同测量方法和筛查选项时肌肉减少症的病例数。对西班牙老年人(n = 272,72%为女性)进行了一项横断面研究。结合EWGSOP2算法中描述步骤所提出的不同测量方法,得到了12种选项(A-L)。在以下三种模型中分别研究了这些选项:(1)使用SARC-F作为初始筛查;(2)不使用SARC-F;(3)使用SARC-CalF代替SARC-F。χ²独立性检验具有统计学意义(χ²(6) = 88.41,P < 0.001),且所使用的算法与肌肉减少症的分类之间的关联为中等(克莱默V系数 = 0.226)。我们得出结论,EWGSOP2的不同测量选项在研究人群中意味着病例发现的差异。此外,应用SARC-F时,被归类为肌肉减少症的人数会减少。最后,当使用SARC-CalF作为筛查时,肌肉减少症患者的病例发现数会减少。因此,临床环境应考虑这些结果,因为这些步骤会使针对肌肉减少症的预防和治疗干预有很大差异。