Peikert Stefanie Anna, Fischer Anil, Kruse Anne Brigitte, Al-Ahmad Ali, Woelber Johan Peter, Vach Kirstin, Braun Andreas, Ratka-Krüger Petra
Department of Operative Dentistry and Periodontology, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Practice Dr. Stefan Bertram, Gewerbegasse 5, 83395 Freilassing, Germany.
Antibiotics (Basel). 2021 Mar 3;10(3):251. doi: 10.3390/antibiotics10030251.
The aim of this randomized, controlled, double-blinded clinical trial was to examine the additional healing effect of transgingival visible light and water-filtered infrared-A (VIS + wIRA) in the treatment of periodontitis patients compared with the standard therapy by subgingival instrumentation (SI). Therefore, forty patients with untreated periodontitis received a non-surgical periodontal treatment. Using a split-mouth study design, one quadrant of the upper jaw was randomly either exposed to VIS + wIRA four times for 20 min within two weeks in addition to SI or received only SI. Three and 6 months after intervention, clinical parameters (probing depths (PDs), clinical attachment level, bleeding on probing (BOP), furcation, tooth mobility, plaque control record, and papilla bleeding index) were re-evaluated. In the presence of PD of 4 mm and positive BOP or PD > 4 mm, SI was performed again. Moreover, the patients were asked about their discomfort using a visual analog scale from 1 to 10 for each side of the maxilla. Statistical analysis demonstrated no differences between quadrants at re-evaluation for clinical parameters ( > 0.05) after 3 and 6 months. Concerning pain perception, patients described less pain on the irradiated side ( = 0.016). In the treatment of patients with periodontitis, VIS + wIRA did not show an additional effect on the clinical outcome after 3 and 6 months. Patients described less pain on the irradiated quadrant after treatment.
这项随机、对照、双盲临床试验的目的是，研究与通过龈下器械操作（SI）进行的标准治疗相比，经龈可见光和水过滤红外A（VIS + wIRA）在牙周炎患者治疗中的额外愈合效果。因此，40例未经治疗的牙周炎患者接受了非手术牙周治疗。采用分口研究设计，上颌的一个象限被随机分配，除SI外，在两周内接受4次VIS + wIRA照射，每次20分钟，或仅接受SI。干预后3个月和6个月，重新评估临床参数（探诊深度（PD）、临床附着水平、探诊出血（BOP）、根分叉病变、牙齿松动度、菌斑控制记录和龈乳头出血指数）。当PD为4 mm且BOP阳性或PD > 4 mm时，再次进行SI。此外，使用1至10的视觉模拟量表询问患者上颌每一侧的不适情况。统计分析表明，3个月和6个月重新评估临床参数时，各象限之间无差异（> 0.05）。关于疼痛感知，患者表示照射侧疼痛较轻（= 0.016）。在牙周炎患者的治疗中，VIS + wIRA在3个月和6个月后对临床结果未显示出额外效果。治疗后，患者表示照射象限的疼痛较轻。
