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甩尾试验中的反应潜伏期取决于尾部皮肤温度。

Response latencies in the tail-flick test depend on tail skin temperature.

作者信息

Berge O G, Garcia-Cabrera I, Hole K

机构信息

Department of Physiology, University of Bergen, Norway.

出版信息

Neurosci Lett. 1988 Apr 12;86(3):284-8. doi: 10.1016/0304-3940(88)90497-1.

DOI:10.1016/0304-3940(88)90497-1
PMID:3380319
Abstract

Tail skin temperatures and tail-flick latencies were simultaneously recorded in male Sprague-Dawley rats exposed to various ambient temperatures (22-30 degrees C). There was a positive correlation between tail skin temperature and ambient temperature and a negative correlation between tail-flick latency and ambient temperature. Importantly, a highly significant negative correlation was present between tail-flick latency and skin temperature, even at constant ambient temperature (22.1 or 23.3 degrees C). Thus, the results of tail-flick testing are highly affected by skin temperature and factors altering the skin temperature must be considered when tail-flick latencies are interpreted in terms of nociception.

摘要

在暴露于不同环境温度(22 - 30摄氏度)下的雄性斯普拉格 - 道利大鼠中,同时记录了尾部皮肤温度和甩尾潜伏期。尾部皮肤温度与环境温度呈正相关,甩尾潜伏期与环境温度呈负相关。重要的是,即使在恒定环境温度(22.1或23.3摄氏度)下,甩尾潜伏期与皮肤温度之间也存在高度显著的负相关。因此,甩尾测试的结果受皮肤温度的影响很大,在根据伤害感受来解释甩尾潜伏期时,必须考虑改变皮肤温度的因素。

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