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利用心电图和多尺度特征连接检测心肌梗死。

Detection of Myocardial Infarction Using ECG and Multi-Scale Feature Concatenate.

机构信息

Department of Biomedical Engineering, Chung Yuan Christian University, Taoyuan City 320314, Taiwan.

Department of Electrical Engineering, Ming Chi University of Technology, New Taipei City 243303, Taiwan.

出版信息

Sensors (Basel). 2021 Mar 9;21(5):1906. doi: 10.3390/s21051906.

Abstract

Diverse computer-aided diagnosis systems based on convolutional neural networks were applied to automate the detection of myocardial infarction (MI) found in electrocardiogram (ECG) for early diagnosis and prevention. However, issues, particularly overfitting and underfitting, were not being taken into account. In other words, it is unclear whether the network structure is too simple or complex. Toward this end, the proposed models were developed by starting with the simplest structure: a multi-lead features-concatenate narrow network (N-Net) in which only two convolutional layers were included in each lead branch. Additionally, multi-scale features-concatenate networks (MSN-Net) were also implemented where larger features were being extracted through pooling the signals. The best structure was obtained via tuning both the number of filters in the convolutional layers and the number of inputting signal scales. As a result, the N-Net reached a 95.76% accuracy in the MI detection task, whereas the MSN-Net reached an accuracy of 61.82% in the MI locating task. Both networks give a higher average accuracy and a significant difference of < 0.001 evaluated by the test compared with the state-of-the-art. The models are also smaller in size thus are suitable to fit in wearable devices for offline monitoring. In conclusion, testing throughout the simple and complex network structure is indispensable. However, the way of dealing with the class imbalance problem and the quality of the extracted features are yet to be discussed.

摘要

基于卷积神经网络的多样化计算机辅助诊断系统被应用于自动检测心电图(ECG)中的心肌梗死(MI),以实现早期诊断和预防。然而,一些问题,特别是过拟合和欠拟合问题,并没有得到考虑。换句话说,不清楚网络结构是过于简单还是过于复杂。为此,提出的模型从最简单的结构开始开发:多导联特征连接窄网络(N-Net),其中每个导联分支仅包含两个卷积层。此外,还实现了多尺度特征连接网络(MSN-Net),通过对信号进行池化来提取更大的特征。通过调整卷积层中的滤波器数量和输入信号尺度的数量来获得最佳结构。结果,N-Net 在 MI 检测任务中达到了 95.76%的准确率,而 MSN-Net 在 MI 定位任务中达到了 61.82%的准确率。两个网络的平均准确率都更高,通过 检验评估,与最先进的方法相比,差异具有统计学意义(<0.001)。这些模型的规模也较小,因此适合用于可穿戴设备进行离线监测。总之,对简单和复杂网络结构进行全面测试是必不可少的。然而,处理类别不平衡问题的方法和提取特征的质量仍有待讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1397/7967244/de6bbbb3bbc3/sensors-21-01906-g001.jpg

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