Department Nursing and Podiatry, Faculty of Health Sciences, Instituto de Investigación Biomédica de Málaga (IBIMA), Ampliación de Campus de Teatinos, University of Malaga, Arquitecto Francisco Peñalosa 3, 29071 Málaga, Spain.
Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Int J Environ Res Public Health. 2021 Mar 1;18(5):2369. doi: 10.3390/ijerph18052369.
Parkinson's disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this study was to evaluate depression in patients with Parkinson's Disease (PD) compared to subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12). Patients with PD were recruited from a center of excellence for Parkinson's disease (cases = 62) and healthy subjects without PD from their relatives and caregivers (control = 62). The Spanish version of Beck's Depression Inventory (BDI) scores and categories were collected. A clear statistically significant difference ( < 0.05) was evident in the BDI scores between both groups. Parkinson's patients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects with BDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences ( < 0.001) for the greater BDI categories in the Parkinson's group compared with healthy subjects. The depression represents an important potential risk for increased symptoms and negative impact among patients with PD compared with healthy subjects.
帕金森病是一种常见的神经退行性疾病，已知会引起与运动器官肌肉骨骼问题相关的运动障碍，以及非运动症状，这些症状被认为对健康、社会功能和行动能力有不良影响。本研究旨在评估帕金森病（PD）患者与无 PD 的受试者之间的抑郁情况。该样本由 124 名参与者组成（平均年龄 69.18 ± 9.12 岁）。PD 患者从帕金森病卓越中心招募（病例组=62 人），无 PD 的健康受试者从其亲属和护理人员中招募（对照组=62 人）。收集了贝克抑郁量表（BDI）的西班牙语版本评分和类别。两组之间的 BDI 评分存在明显的统计学差异（<0.05）。与 BDI=7.03±6.99 分的健康对照组相比，帕金森病患者的 BDI 得分较差，为 15.48±7.24 分。关于 BDI 类别，帕金森病组的较大 BDI 类别存在统计学差异（<0.001），与健康对照组相比。与健康对照组相比，抑郁在 PD 患者中代表了一个重要的潜在风险，会增加症状和负面影响。
