Lobo Flávia C M, Franco Albina R, Fernandes Emanuel M, Reis Rui L
3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark-Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Barco/Guimarães, Portugal.
ICVS/3B's-PT Government Associate Laboratory, 4805-017 Braga/Guimarães, Portugal.
Molecules. 2021 Mar 20;26(6):1749. doi: 10.3390/molecules26061749.
Pathogenic microbes are a major source of health and environmental problems, mostly due to their easy proliferation on most surfaces. Currently, new classes of antimicrobial agents are under development to prevent microbial adhesion and biofilm formation. However, they are mostly from synthetic origin and present several disadvantages. The use of natural biopolymers such as cellulose, hemicellulose, and lignin, derived from lignocellulosic materials as antimicrobial agents has a promising potential. Lignocellulosic materials are one of the most abundant natural materials from renewable sources, and they present attractive characteristics, such as low density and biodegradability, are low-cost, high availability, and environmentally friendly. This review aims to provide new insights into the current usage and potential of lignocellulosic materials (biopolymer and fibers) as antimicrobial materials, highlighting their future application as a novel drug-free antimicrobial polymer.
致病微生物是健康和环境问题的主要来源，这主要是由于它们易于在大多数表面上增殖。目前，新型抗菌剂正在研发中，以防止微生物粘附和生物膜形成。然而，它们大多来源于合成，存在一些缺点。使用源自木质纤维素材料的天然生物聚合物，如纤维素、半纤维素和木质素作为抗菌剂具有广阔的前景。木质纤维素材料是可再生资源中最丰富的天然材料之一，它们具有吸引人的特性，如低密度、可生物降解、低成本、高可用性且环保。本综述旨在为木质纤维素材料（生物聚合物和纤维）作为抗菌材料的当前用途和潜力提供新的见解，突出其作为新型无药抗菌聚合物的未来应用。
