Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.
Teratology Information Service, Pharmacovigilance Centre Lareb, 5237 MH 's Hertogenbosch, The Netherlands.
Int J Environ Res Public Health. 2021 Mar 24;18(7):3367. doi: 10.3390/ijerph18073367.
The COVID-19 pandemic may be of particular concern for pregnant and breastfeeding women. We aimed to explore their beliefs about the coronavirus and COVID-19 vaccine willingness and to assess the impact of the pandemic on perinatal experiences and practices. A multinational, cross-sectional, web-based study was performed in six European countries between April and July 2020. The anonymous survey was promoted via social media. In total, 16,063 women participated (including 6661 pregnant and 9402 breastfeeding women). Most responses were collected from Belgium (44%), Norway (18%) and the Netherlands (16%), followed by Switzerland (11%), Ireland (10%) and the UK (3%). Despite differences between countries, COVID-19 vaccine hesitancy was identified among 40-50% of the respondents at the end of the first wave of the pandemic and was higher among pregnant women. Education level and employment status were associated with vaccine hesitancy. The first wave had an adverse impact on pregnancy experiences and disrupted access to health services and breastfeeding support for many women. In the future, access to health care and support should be maintained at all times. Evidence-based and tailored information on COVID-19 vaccines should also be provided to pregnant and breastfeeding women to avoid unfounded concerns about the vaccines and to support shared decision making in this population.
COVID-19 大流行可能特别令孕妇和哺乳期妇女感到担忧。我们旨在探讨她们对冠状病毒和 COVID-19 疫苗的看法、意愿,评估大流行对围产期经历和实践的影响。2020 年 4 月至 7 月期间,在六个欧洲国家进行了一项多国家、横断面、基于网络的研究。这项匿名调查是通过社交媒体进行宣传的。共有 16063 名妇女参与了这项调查(包括 6661 名孕妇和 9402 名哺乳期妇女)。大部分回复来自比利时(44%)、挪威(18%)和荷兰(16%),其次是瑞士(11%)、爱尔兰(10%)和英国(3%)。尽管各国之间存在差异,但在大流行第一波期间,40-50%的受访者对 COVID-19 疫苗犹豫不决,孕妇中这一比例更高。教育程度和就业状况与疫苗犹豫有关。第一波大流行对怀孕经历产生了不利影响,并使许多妇女难以获得医疗服务和母乳喂养支持。在未来,应随时保持获得医疗保健和支持的机会。还应向孕妇和哺乳期妇女提供有关 COVID-19 疫苗的循证和定制信息,以避免对疫苗的无端担忧,并支持该人群的共同决策。