Chirollo Claudia, Nocera Francesca Paola, Piantedosi Diego, Fatone Gerardo, Della Valle Giovanni, De Martino Luisa, Cortese Laura
Department of Veterinary Medicine and Animal Productions, University of Naples, "Federico II", Via Delpino 1, 80137 Naples, Italy.
Animals (Basel). 2021 Mar 23;11(3):913. doi: 10.3390/ani11030913.
Over recent decades, antimicrobial resistance has been considered one of the most relevant issues of public health. The aim of our study was to evaluate the differences related to the prescription of antimicrobials at the University Veterinary Teaching Hospital, before and after the mandatory use of veterinary electronic prescription (VEP). In particular, the consumption of antimicrobials was examined, especially taking into consideration the recommendations of prudent use. A comparison of data collected before and after the use of electronic prescription highlighted that during the period chosen for the study, the choice of antimicrobial molecules was appropriate, favoring those of "first" and "second line." However, prescription and the use of some molecules not registered for veterinary medicine were observed in the period before VEP. Broad-spectrum antimicrobials, including penicillins with -lactamase inhibitors, as well as first-generation cephalosporins and fluoroquinolones, were the most frequently prescribed compounds. There are few studies conducted in Italy aimed at investigating the use of antimicrobials in companion animals under field conditions and with particular regard to prudent use recommendations. This type of study underlines the importance of electronic medical recording in veterinary practice and, above all, its usefulness in monitoring the use of certain antimicrobial agents classified as of critical importance in human medicine.
近几十年来，抗菌药物耐药性一直被视为公共卫生领域最相关的问题之一。我们研究的目的是评估在强制使用兽医电子处方（VEP）之前和之后，大学兽医教学医院抗菌药物处方的差异。特别是，对抗菌药物的使用情况进行了检查，尤其考虑了谨慎使用的建议。对使用电子处方前后收集的数据进行比较后发现，在研究选定的时间段内，抗菌药物分子的选择是合适的，倾向于“一线”和“二线”药物。然而，在VEP实施前的时间段内，观察到了一些未注册用于兽医学的分子的处方和使用情况。包括含β-内酰胺酶抑制剂的青霉素、第一代头孢菌素和氟喹诺酮类在内的广谱抗菌药物是最常开具的化合物。很少有研究旨在调查伴侣动物在实际情况下抗菌药物的使用情况，特别是关于谨慎使用建议的情况。这类研究强调了电子病历在兽医实践中的重要性，最重要的是，它在监测某些被归类为对人类医学至关重要的抗菌药物使用方面的有用性。
