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Fluoride-cleavable biotinylation phosphoramidite for 5'-end-labeling and affinity purification of synthetic oligonucleotides.
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Solid-phase synthesis and hybridization properties of DNA containing sulfide-linked dinucleosides.
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Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA.
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Approaches to antiviral drug development.
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Sequence dependent effects in methylphosphonate deoxyribonucleotide double and triple helical complexes.
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Phosphoramidate analogs of oligonucleotides.
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Synthesis of carbonate analogs of dinucleosides. 3'-Thymidinyl 5'-thymidinyl carbonate, 3'-thymidinyl 5'-(5-fluoro-2'-deoxyuridinyl) carbonate, and 3'-(5-fluoro-2'-deoxyuridinyl) 5'-thymidinyl carbonate.
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Synthesis of cyclic silyl nucleosides having bulky groups on the silicon atom.
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Carbamate analogues of oligonucleotides.
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Nonionic nucleic acid analogues. Synthesis and characterization of dideoxyribonucleoside methylphosphonates.
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Synthesis and enzymatic properties of deoxyribooligonucleotides containing methyl and phenylphosphonate linkages.
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