Hernández-Rodríguez Carlos Javier, Fukumitsu Hideki, Ruiz-Fortes Pedro, Soto-Negro Roberto, Merino-Suárez María, Piñero David P
Department of Ophthalmology, Vithas Medimar International Hospital, 03016 Alicante, Spain.
Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 Alicante, Spain.
Vision (Basel). 2021 Mar 23;5(1):15. doi: 10.3390/vision5010015.
A retrospective study was conducted to evaluate preliminarily the efficacy of perceptual learning (PL) visual training in medium-term follow-up with a specific software (Amblyopia iNET, Home Therapy Systems Inc., Gold Canyon, AZ, USA) for visual acuity (VA) and contrast sensitivity (CS) recovering in a sample of 14 moderate to severe amblyopic subjects with a previously unsuccessful outcome or failure with patching (PL Group). This efficacy was compared with that achieved in a patching control group (13 subjects, Patching 2). At one-month follow-up, a significant VA improvement in the amblyopic eye (AE) was observed in both groups, with no significant differences between them. Additionally, CS was measured in PL Group and exhibited a significant improvement in the AE one month after the beginning of treatment for 3, 6, 12, and 18 cycles/º ( = 0.003). Both groups showed long-lasting retention of visual improvements. A combined therapy of PL-based visual training and patching seems to be effective for improving VA in children with amblyopia who did not recover vision with patching alone or had a poor patching compliance. This preliminary outcome should be confirmed in future clinical trials.
进行了一项回顾性研究，以初步评估使用特定软件（美国亚利桑那州黄金峡谷市Home Therapy Systems Inc.公司的弱视iNET）进行感知学习（PL）视觉训练对14例中度至重度弱视患者的视力（VA）和对比敏感度（CS）恢复的中期随访效果，这些患者之前接受遮盖治疗未成功或失败（PL组）。将该效果与遮盖对照组（13例患者，遮盖2组）的效果进行比较。在1个月的随访中，两组弱视眼（AE）的视力均有显著改善，且两组之间无显著差异。此外，在PL组测量了对比敏感度，在治疗开始1个月后，AE的对比敏感度在3、6、12和18周期/度时均有显著改善（P = 0.003）。两组的视力改善均具有长期持续性。基于PL的视觉训练与遮盖的联合治疗似乎对改善弱视儿童的视力有效，这些儿童单独使用遮盖治疗未能恢复视力或遮盖依从性差。这一初步结果应在未来的临床试验中得到证实。
