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三焦点衍射人工晶状体植入患者新型视觉康复计划临床益处的初步评估:一项盲法随机安慰剂对照临床试验

Preliminary Evaluation of the Clinical Benefit of a Novel Visual Rehabilitation Program in Patients Implanted with Trifocal Diffractive Intraocular Lenses: A Blinded Randomized Placebo-Controlled Clinical Trial.

作者信息

Piñero David P, Molina-Martin Ainhoa, Ramón María L, Rincón José L, Fernández Cristian, de Fez Dolores, Arenillas Juan F, Leal-Vega Luis, Coco-Martín María Begoña, Maldonado Miguel J

机构信息

Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 Alicante, Spain.

Department of Ophthalmology, Vithas Medimar International Hospital, 03016 Alicante, Spain.

出版信息

Brain Sci. 2021 Sep 8;11(9):1181. doi: 10.3390/brainsci11091181.

DOI:10.3390/brainsci11091181
PMID:34573202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8464827/
Abstract

The authors of this study evaluated the potential benefit on visual performance of a novel 3 week visual rehabilitation program based on the use of Gabor patches in patients undergoing bilateral cataract surgery with the implantation of two models of trifocal diffractive intraocular lens (IOL). A total of 30 patients were randomly assigned to two groups: a study group (15 patients) that used a videogame based on Gabor patches and a placebo group (15 patients) that used a videogame without specific stimuli for improving visual performance. No statistically significant differences between groups were found in distance, intermediate, and near post-training visual acuity ( ≥ 0.15). Significantly better distance contrast sensitivity (CS) was found for the spatial frequencies of 6 ( = 0.02) and 12 cpd ( = 0.01) in the study group. Likewise, significantly better values of near CS were found in the study group compared to the placebo group for the spatial frequency of 1.5 cpd ( = 0.02). In conclusion, a 3 week visual rehabilitation program based on the use of Gabor patches in the immediate postoperative period after the bilateral implantation of trifocal diffractive IOLs seems to be beneficial for improving both distance and near visual performance achieved with the implant.

摘要

本研究的作者评估了一项为期3周的新型视觉康复计划对视觉表现的潜在益处,该计划基于对接受双侧白内障手术并植入两种三焦点衍射人工晶状体(IOL)模型的患者使用Gabor斑块。总共30名患者被随机分为两组:一组是研究组(15名患者),使用基于Gabor斑块的电子游戏;另一组是安慰剂组(15名患者),使用没有特定改善视觉表现刺激的电子游戏。训练后,两组在远、中、近视力(≥0.15)方面未发现统计学上的显著差异。研究组在空间频率为6(P = 0.02)和12 cpd(P = 0.01)时,远视力对比敏感度(CS)显著更好。同样,研究组在空间频率为1.5 cpd时,近CS值与安慰剂组相比显著更好(P = 0.02)。总之,在双侧植入三焦点衍射IOL后的术后早期,基于使用Gabor斑块的3周视觉康复计划似乎有利于改善植入后获得的远视力和近视力表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/e6d6eaf2657c/brainsci-11-01181-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/26975695a6a5/brainsci-11-01181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/b279ae31fbe4/brainsci-11-01181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/09e6d9da2b07/brainsci-11-01181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/e6d6eaf2657c/brainsci-11-01181-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/26975695a6a5/brainsci-11-01181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/b279ae31fbe4/brainsci-11-01181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/09e6d9da2b07/brainsci-11-01181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e2c/8464827/e6d6eaf2657c/brainsci-11-01181-g004.jpg

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J Refract Surg. 2021 Jul;37(7):460-465. doi: 10.3928/1081597X-20210420-01. Epub 2021 Jul 1.
2
Depth of field measures in pseudophakic eyes implanted with different type of presbyopia-correcting IOLS.不同类型的老视矫正型人工晶状体植入术后眼的景深测量。
Sci Rep. 2021 Jun 8;11(1):12081. doi: 10.1038/s41598-021-91654-w.
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Virtual Reality Visual Training in an Adult Patient with Anisometropic Amblyopia: Visual and Functional Magnetic Resonance Outcomes.
成人屈光参差性弱视患者的虚拟现实视觉训练:视觉及功能磁共振成像结果
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Efficacy of Perceptual Learning-Based Vision Training as an Adjuvant to Occlusion Therapy in the Management of Amblyopia: A Pilot Study.基于感知学习的视觉训练作为弱视遮盖治疗辅助手段的疗效:一项初步研究
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Visual and Patient-Reported Outcomes of a Diffractive Trifocal Intraocular Lens Compared with Those of a Monofocal Intraocular Lens.对比单焦点人工晶状体,衍射型三焦点人工晶状体的视觉和患者报告结果。
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