一项关于抗坏血酸治疗普通感冒的试验。
A trial of ascorbic acid in the treatment of the common cold.
作者信息
Tyrrell D A, Craig J W, Meada T W, White T
出版信息
Br J Prev Soc Med. 1977 Sep;31(3):189-91. doi: 10.1136/jech.31.3.189.
A randomised controlled trial was carried out to study the effect of 10 g of ascorbic acid taken during the first 2 1/2 days on the symptoms of the common cold. Altogether 1524 volunteers were recruited from a number of working groups in different parts of the country; 482 developed colds. There was no evidence that upper respiratory or general constitutional symptoms were alleviated by ascorbic acid. Among the men who had any colds at all, significantly fewer on active than on placebo treatment had two or more colds; however, this effect was not seen in women. Ascorbic acid is of no value in the treatment of the common cold; its preventive effect, if any, is not such as to justify advising its general use as a prophylactic measure.
进行了一项随机对照试验，以研究在感冒头2.5天服用10克抗坏血酸对普通感冒症状的影响。总共从该国不同地区的多个工作组招募了1524名志愿者；其中482人患了感冒。没有证据表明抗坏血酸能缓解上呼吸道症状或全身症状。在所有患感冒的男性中，接受活性治疗的人患两次或更多次感冒的人数明显少于接受安慰剂治疗的人；然而，在女性中未观察到这种效果。抗坏血酸对治疗普通感冒没有价值；其预防作用（如果有的话）不足以证明建议将其作为预防措施普遍使用是合理的。
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