School of Nursing, Hanyang University, Seoul 04763, Korea.
Int J Environ Res Public Health. 2021 Mar 12;18(6):2896. doi: 10.3390/ijerph18062896.
It is necessary to engage in an appropriate level of physical activity to improve the prognoses of colorectal cancer patients, yet no guidelines currently exist. The goals of this systematic review are to determine the impact of levels of physical activity on the prognoses of colorectal cancer patients and to suggest recommended guidelines for levels of physical activity.
This systematic review was conducted along PRISMA guidelines. Per the inclusion criteria, papers published in academic journals in English from 2010 to 2019 were selected. A literature search was performed on PubMed (Medline), and the results of the selected studies were qualitatively synthesized.
Of the 13 cohort studies included in this systematic review, most studies were conducted in the United States (N = 7). Immobility or low levels of physical activity adversely affected the prognoses of colorectal cancer patients. Contrarily, high levels of physical activity increased the survival rate in people with colorectal cancer.
For colorectal cancer patients, a level of physical activity of 17.5 to 35 MET hours per week is strongly recommended, which has been shown to reduce mortality by approximately 30 to 40%. Patients with limited physical capacity should maintain a minimum level of physical activity (≥3.5 MET hours/week).
为改善结直肠癌患者的预后,需要进行适当水平的身体活动,但目前尚无相关指南。本系统评价的目的是确定身体活动水平对结直肠癌患者预后的影响,并为身体活动水平推荐建议性指南。
本系统评价根据 PRISMA 指南进行。根据纳入标准,选择了 2010 年至 2019 年期间以英文发表在学术期刊上的论文。在 PubMed(Medline)上进行了文献检索,并对入选研究的结果进行了定性综合。
在本系统评价纳入的 13 项队列研究中,大多数研究在美国进行(N=7)。不活动或低水平的身体活动对结直肠癌患者的预后产生不利影响。相反,高水平的身体活动增加了结直肠癌患者的生存率。
对于结直肠癌患者,强烈推荐每周进行 17.5 至 35 MET 小时的身体活动,这已被证明可使死亡率降低约 30%至 40%。身体活动能力有限的患者应保持最低水平的身体活动(≥3.5 MET 小时/周)。