Wajs-Bonikowska Anna, Malarz Janusz, Szoka Łukasz, Kwiatkowski Paweł, Stojakowska Anna
Institute of General Food Chemistry, Faculty of Biotechnology and Food Sciences, Łódź University of Technology, Stefanowskiego Street 4/10, 90-924 Łódź, Poland.
Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.
Molecules. 2021 Mar 26;26(7):1883. doi: 10.3390/molecules26071883.
L., one of the two species occurring in Europe, in the Far East and India, found use as a vegetable and a traditional medicinal remedy for several ailments. In the present study, compositions of essential oils distilled from roots and shoots of plants, cultivated in the open field, have been studied by GC-MS-FID supported by NMR spectroscopy. The analyses led to the identification of 120 compounds in total, of which 115 were found in aerial parts and 37 in roots of the plants. The major constituents found in the oil from shoots were: α-pinene (35%) and 2,5-dimethoxy--cymene (thymohydroquinone dimethyl ether, 12%), whereas 2,5-dimethoxy--cymene (55%), thymyl isobutyrate (9%) and thymol methyl ether (8%) predominated in the essential oil obtained from the roots. Antibacterial and cytotoxic activities of the essential oils distilled from were also tested. The essential oil from aerial parts of the plant demonstrated good inhibitory activity against ATCC 29213 and ATCC 25922 (MIC: 15.6 μL/mL).
L.是在欧洲、远东和印度出现的两个物种之一，被用作蔬菜和治疗多种疾病的传统药物。在本研究中，通过核磁共振光谱辅助的气相色谱-质谱-火焰离子化检测法，对在露天田地种植的植物的根和茎中蒸馏得到的精油成分进行了研究。分析总共鉴定出120种化合物，其中115种存在于植物地上部分，37种存在于植物根部。茎部精油中的主要成分是：α-蒎烯（35%）和2,5-二甲氧基-对异丙基苯（百里氢醌二甲醚，12%），而从根部获得的精油中，2,5-二甲氧基-对异丙基苯（55%）、异丁酸百里酯（9%）和百里香酚甲醚（8%）占主导。还测试了从该植物蒸馏得到的精油的抗菌和细胞毒性活性。植物地上部分的精油对金黄色葡萄球菌ATCC 29213和大肠杆菌ATCC 25922表现出良好的抑制活性（最低抑菌浓度：15.6 μL/mL）。
