University of Lausanne, 1015, Lausanne, Switzerland.
Swiss Federal Institute of Technology in Lausanne (EPFL), 1015, Lausanne, Switzerland.
ChemMedChem. 2021 Aug 5;16(15):2288-2314. doi: 10.1002/cmdc.202100079. Epub 2021 Jun 22.
CoVID-19 is a multi-symptomatic disease which has made a global impact due to its ability to spread rapidly, and its relatively high mortality rate. Beyond the heroic efforts to develop vaccines, which we do not discuss herein, the response of scientists and clinicians to this complex problem has reflected the need to detect CoVID-19 rapidly, to diagnose patients likely to show adverse symptoms, and to treat severe and critical CoVID-19. Here we aim to encapsulate these varied and sometimes conflicting approaches and the resulting data in terms of chemistry and biology. In the process we highlight emerging concepts, and potential future applications that may arise out of this immense effort.
新型冠状病毒肺炎（COVID-19）是一种多症状疾病，由于其具有快速传播的能力和相对较高的死亡率，因此在全球范围内产生了影响。除了我们在此处不讨论的开发疫苗的英勇努力之外，科学家和临床医生对这一复杂问题的反应反映了需要快速检测 COVID-19，诊断可能出现不良症状的患者，并治疗严重和危急的 COVID-19。在这里，我们旨在从化学和生物学的角度概括这些不同的、有时相互冲突的方法和由此产生的数据。在此过程中，我们强调了由此巨大努力中可能出现的新出现的概念和潜在的未来应用。
