Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Nutr Metab Cardiovasc Dis. 2021 May 6;31(5):1391-1400. doi: 10.1016/j.numecd.2021.01.001. Epub 2021 Jan 21.
Obesity has been linked to the development of hypertension, but the comparison of relationships between different obesity parameters with hypertension are scarcely studied with nationally representative Chinese adults samples. We sought to compare the predictive strengths of different obesity indicators to hypertension.
Data in this study were obtained from the Chinese National Stroke Prevention Project with a nationally representative sample of Chinese aged 40 years and older. A total of 162,880 individuals were included. Multi-level analyses and Receiver Operating Characteristic (ROC) curves were used to examine the risk of hypertension in relation to different obesity parameters, including body mass index (BMI), waist circumference (WC), lipid accumulation product index (LAP), visceral adiposity index (VAI), and body adiposity index (BAI). As results, the BMI, WC, LAP, VAI, and BAI were positively associated with the risk of hypertension (P < 0.001). In total, BMI had the strongest association with hypertension when compared with other obesity indicators, and one SD up of BMI would increase the risk of hypertension by 53.9% (95% CI: 1.514-1.566). For men, WC was most associated with hypertension, and one SD up of WC would increase the risk of hypertension by 73.3% (95% CI: 1.685-1.782). For women, BMI showed the strongest predictive power, one SD up of BMI would increase the risk of hypertension by 51.0% (95% CI: 1.479-1.543).
BMI, WC, LAP, VAI, and BAI are all positively corrected to hypertension, but gender disparities should be considered in predicting hypertension by obesity indicators.
肥胖与高血压的发生有关，但具有全国代表性的中国成年人样本中，很少有研究比较不同肥胖参数与高血压之间的关系。我们旨在比较不同肥胖指标预测高血压的强度。
本研究数据来自中国国家卒中预防项目，该项目采用具有全国代表性的 40 岁及以上中国成年人样本。共纳入 162880 人。多水平分析和接收者操作特征（ROC）曲线用于检查不同肥胖参数与高血压相关的风险，包括体重指数（BMI）、腰围（WC）、脂肪堆积产物指数（LAP）、内脏脂肪指数（VAI）和身体脂肪指数（BAI）。结果显示，BMI、WC、LAP、VAI 和 BAI 与高血压风险呈正相关（P<0.001）。总的来说，与其他肥胖指标相比，BMI 与高血压的相关性最强，BMI 增加一个标准差会使高血压的风险增加 53.9%（95%CI：1.514-1.566）。对于男性，WC 与高血压的相关性最强，WC 增加一个标准差会使高血压的风险增加 73.3%（95%CI：1.685-1.782）。对于女性，BMI 显示出最强的预测能力，BMI 增加一个标准差会使高血压的风险增加 51.0%（95%CI：1.479-1.543）。
BMI、WC、LAP、VAI 和 BAI 与高血压均呈正相关，但在预测肥胖指标引起的高血压时应考虑性别差异。
