Harrist T J, Kalisher L
Cancer. 1977 Dec;40(6):3102-6. doi: 10.1002/1097-0142(197712)40:6<3102::aid-cncr2820400652>3.0.co;2-n.
A metastasis from a bronchial carcinoid tumor presented as an isolated breast mass in a 58-year-old female. A review of the English literature revealed four cases of metastatic carcinoid to the breast that presented as an isolated breast mass. In each case, radical mastectomy was performed after the lesion had been interpreted clinically and pathologically as a primary carcinoma. When the primary tumor was excised, all cases had either regional lymph node or liver involvement. A mass was the usual presenting sign of the metastatic deposit. No metastasis was reported to be greater than 2 cm in diameter. No axillary lymph nodes were reported to contain tumor. Frozen section preparations may not be adequate to differentiate a primary carcinoma of the breast from a metastatic carcinoid tumor, thereby necessitating permanent sections, special stains, review of previously resected neoplasms, or electron microscopy. The first mammogram of a metastatic carcinoid to the breast is reported with this case.
一名58岁女性的支气管类癌转移瘤表现为孤立性乳腺肿块。对英文文献的回顾显示,有4例类癌转移至乳腺,均表现为孤立性乳腺肿块。在每例病例中,病变经临床和病理诊断为原发性癌后均行根治性乳房切除术。当切除原发性肿瘤时,所有病例均有区域淋巴结或肝脏受累。肿块是转移灶的常见表现体征。据报道,转移灶直径均不超过2cm。未报道腋窝淋巴结有肿瘤。冰冻切片可能不足以区分乳腺原发性癌与转移性类癌肿瘤,因此需要进行永久性切片、特殊染色、回顾先前切除的肿瘤或进行电子显微镜检查。本文报道了首例乳腺转移性类癌的乳房X线照片。