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乳腺转移:恶性类癌肿瘤的一种罕见表现。

Breast metastasis: an unusual manifestation of a malignant carcinoid tumor.

作者信息

Harrist T J, Kalisher L

出版信息

Cancer. 1977 Dec;40(6):3102-6. doi: 10.1002/1097-0142(197712)40:6<3102::aid-cncr2820400652>3.0.co;2-n.

DOI:10.1002/1097-0142(197712)40:6<3102::aid-cncr2820400652>3.0.co;2-n
PMID:338142
Abstract

A metastasis from a bronchial carcinoid tumor presented as an isolated breast mass in a 58-year-old female. A review of the English literature revealed four cases of metastatic carcinoid to the breast that presented as an isolated breast mass. In each case, radical mastectomy was performed after the lesion had been interpreted clinically and pathologically as a primary carcinoma. When the primary tumor was excised, all cases had either regional lymph node or liver involvement. A mass was the usual presenting sign of the metastatic deposit. No metastasis was reported to be greater than 2 cm in diameter. No axillary lymph nodes were reported to contain tumor. Frozen section preparations may not be adequate to differentiate a primary carcinoma of the breast from a metastatic carcinoid tumor, thereby necessitating permanent sections, special stains, review of previously resected neoplasms, or electron microscopy. The first mammogram of a metastatic carcinoid to the breast is reported with this case.

摘要

一名58岁女性的支气管类癌转移瘤表现为孤立性乳腺肿块。对英文文献的回顾显示,有4例类癌转移至乳腺,均表现为孤立性乳腺肿块。在每例病例中,病变经临床和病理诊断为原发性癌后均行根治性乳房切除术。当切除原发性肿瘤时,所有病例均有区域淋巴结或肝脏受累。肿块是转移灶的常见表现体征。据报道,转移灶直径均不超过2cm。未报道腋窝淋巴结有肿瘤。冰冻切片可能不足以区分乳腺原发性癌与转移性类癌肿瘤,因此需要进行永久性切片、特殊染色、回顾先前切除的肿瘤或进行电子显微镜检查。本文报道了首例乳腺转移性类癌的乳房X线照片。

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1
Breast metastasis: an unusual manifestation of a malignant carcinoid tumor.乳腺转移:恶性类癌肿瘤的一种罕见表现。
Cancer. 1977 Dec;40(6):3102-6. doi: 10.1002/1097-0142(197712)40:6<3102::aid-cncr2820400652>3.0.co;2-n.
2
Solitary breast metastasis as first manifestation of ovarian carcinoid tumor.孤立性乳腺转移作为卵巢类癌肿瘤的首发表现。
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Solitary breast metastasis: first manifestation of an occult carcinoid of the ileum.孤立性乳腺转移:回肠隐匿性类癌的首发表现。
Virchows Arch A Pathol Anat Histol. 1980;386(1):117-24. doi: 10.1007/BF00432649.
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Bronchial carcinoid tumor metastatic to the breast.转移至乳腺的支气管类癌肿瘤。
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Carcinoid tumor metastatic to the breast.类癌转移至乳腺。
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Occult breast carcinoma presenting with axillary lymph node metastases: report of two cases.以腋窝淋巴结转移为表现的隐匿性乳腺癌:2例报告。
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[Carcinoma with carcinoid differentiation. Differential diagnostic interpretation of an unusual malignant breast tumor].[伴有类癌分化的癌。一种不寻常的乳腺恶性肿瘤的鉴别诊断解读]
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引用本文的文献

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Neuroendocrine Tumor Metastases to the Breast: A Case Report and Review of the Literature.神经内分泌肿瘤转移至乳腺:一例病例报告及文献综述
Cureus. 2023 Jun 20;15(6):e40703. doi: 10.7759/cureus.40703. eCollection 2023 Jun.
2
Breast Metastasis Arising from Ileal Neuroendocrine Tumor: an Unusual Presentation.回肠神经内分泌肿瘤引起的乳腺转移:一种不寻常的表现。
Nucl Med Mol Imaging. 2023 Aug;57(4):201-205. doi: 10.1007/s13139-023-00792-8. Epub 2023 Feb 28.
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The rare entity of bilateral and unilateral neuroendocrine metastases to the breast: a case series and literature review.
双侧及单侧乳腺神经内分泌转移这一罕见实体:病例系列及文献综述
Ecancermedicalscience. 2020 Oct 15;14:1123. doi: 10.3332/ecancer.2020.1123. eCollection 2020.
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Occult Primary Neuroendocrine Tumor Metastasis to the Breast Detected on Screening Mammogram.筛查乳腺钼靶检查发现隐匿性原发性神经内分泌肿瘤转移至乳腺
J Clin Imaging Sci. 2016 Sep 29;6:41. doi: 10.4103/2156-7514.191439. eCollection 2016.
5
Comparison of metastatic neuroendocrine neoplasms to the breast and primary invasive mammary carcinomas with neuroendocrine differentiation.转移性神经内分泌肿瘤与具有神经内分泌分化的原发性浸润性乳腺癌的比较。
Mod Pathol. 2016 Aug;29(8):788-98. doi: 10.1038/modpathol.2016.69. Epub 2016 Apr 29.
6
Breast metastasis as the first clinical manifestation of ileal neuroendocrine tumor. A challenging diagnosis with relevant clinical implications.乳腺转移作为回肠神经内分泌肿瘤的首发临床表现。一项具有相关临床意义的具有挑战性的诊断。
Endocr Pathol. 2015 May;26(2):145-51. doi: 10.1007/s12022-015-9371-x.
7
Solid neuroendocrine breast carcinoma: mammographic and sonographic features in thirteen cases.实性乳腺神经内分泌癌:13例的钼靶和超声特征
Chin J Cancer. 2012 Nov;31(11):549-56. doi: 10.5732/cjc.011.10370. Epub 2012 May 23.
8
Pancreatic Neuroendocrine Carcinoma Metastatic to the Breast as Part of the Multiple Endocrine Neoplasia Type 1 Syndrome.作为多发性内分泌腺瘤1型综合征一部分的胰腺神经内分泌癌转移至乳腺。
Endocr Pathol. 1997 Autumn;8(3):251-258. doi: 10.1007/BF02738793.
9
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J Clin Pathol. 1988 Feb;41(2):171-2. doi: 10.1136/jcp.41.2.171.