Ophthalmology Department, University of Health Sciences Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Rom J Ophthalmol. 2021 Jan-Mar;65(1):73-75. doi: 10.22336/rjo.2021.14.
Iodine is an essential mineral that is necessary for the synthesis of thyroid hormones, which can cause many diseases in the body. The application of adding potassium iodate to table salts started in Turkey in 1998. High doses of iodate cause retinal toxicity, leading to significant vision loss. A 42-year-old paranoid schizophrenic patient who attempted suicide with pure iodine was admitted with bilateral vision loss. Widespread retinal pigment epithelium (RPE), ellipsoid zone (EZ) and interdigitation zone (IZ) damage were present in the optical coherence tomography (OCT) assessment. Fundus autofluorescence (FAF) findings, which included hypoautofluorescence areas that supported this condition, were also found. In conclusion, iodate in high doses is toxic on RPE, EZ and IZ. This situation could be irreversible depending on the dose.
碘是一种必需的矿物质,对于甲状腺激素的合成是必要的,而甲状腺激素可以在体内引起许多疾病。1998 年,在土耳其开始将碘酸钾添加到食盐中。高剂量的碘酸盐会引起视网膜毒性,导致明显的视力丧失。一名 42 岁的偏执型精神分裂症患者试图用纯碘自杀,他因双眼视力丧失而入院。光学相干断层扫描(OCT)评估显示广泛的视网膜色素上皮(RPE)、椭圆区(EZ)和内插区(IZ)损伤。还发现眼底自发荧光(FAF)检查结果,包括支持这种情况的低自发荧光区域。总之,高剂量的碘酸盐对 RPE、EZ 和 IZ 有毒性。这种情况可能是不可逆的,具体取决于剂量。